USP2 in complex with ubiquitin

Summary for 2HD5

Related1NB8 1NBF 2AYN 2AYO
DescriptorUbiquitin carboxyl-terminal hydrolase 2, Polyubiquitin, ZINC ION, ... (4 entities in total)
Functional Keywordsdeubiquitinating protease, cysteine protease, substrate enzyme complex, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm . Isoform 4: Nucleus  O75604
Total number of polymer chains2
Total molecular weight50065.13
Renatus, M.,Kroemer, M. (deposition date: 2006-06-20, release date: 2006-08-15, Last modification date: 2017-10-18)
Primary citation
Renatus, M.,Parrado, S.G.,D'Arcy, A.,Eidhoff, U.,Gerhartz, B.,Hassiepen, U.,Pierrat, B.,Riedl, R.,Vinzenz, D.,Worpenberg, S.,Kroemer, M.
Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2.
Structure, 14:1293-1302, 2006
PubMed: 16905103 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2006.06.012
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23090.5%3.7%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report