8CAF

N8C_Fab3b in complex with NEDD8-CUL1(WHB)

Summary for 8CAF

• Entry DOI: 10.2210/pdb8caf/pdb
• Descriptor: Fab Light Chain, Fab Heavy Chain, Cullin-1, ... (4 entities in total)
• Functional Keywords: nedd8, cullin-ring ligase, ubiquitin, antibody, cell cycle
• Biological source: Homo sapiens; More
• Total number of polymer chains: 8
• Total formula weight: 128531.14

Authors

Duda, D.M.,Yanishevski, D.,Henneberg, L.T.,Schulman, B.A. (deposition date: 2023-01-24, release date: 2023-09-13, Last modification date: 2023-12-06)

• Primary citation: Henneberg, L.T.,Singh, J.,Duda, D.M.,Baek, K.,Yanishevski, D.,Murray, P.J.,Mann, M.,Sidhu, S.S.,Schulman, B.A.; Activity-based profiling of cullin-RING E3 networks by conformation-specific probes.; Nat.Chem.Biol., 19:1513-1523, 2023; PubMed: 37653169; DOI: 10.1038/s41589-023-01392-5

Experimental method

X-RAY DIFFRACTION (2.66 Å)