3F5H
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![BU of 3f5h by Molmil](/molmil-images/mine/3f5h) | Crystal structure of fused docking domains from PikAIII and PikAIV of the pikromycin polyketide synthase | 分子名称: | SODIUM ION, Type I polyketide synthase PikAIII, Type I polyketide synthase PikAIV fusion protein | 著者 | Buchholz, T.J, Geders, T.W, Bartley, F.E, Reynolds, K.A, Smith, J.L, Sherman, D.H. | 登録日 | 2008-11-03 | 公開日 | 2009-01-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. Acs Chem.Biol., 4, 2009
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4D98
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![BU of 4d98 by Molmil](/molmil-images/mine/4d98) | Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group H32 at pH 7.5 | 分子名称: | CHLORIDE ION, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ... | 著者 | Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. | 登録日 | 2012-01-11 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4D9H
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![BU of 4d9h by Molmil](/molmil-images/mine/4d9h) | Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with adenosine | 分子名称: | ADENOSINE, Purine nucleoside phosphorylase deoD-type | 著者 | Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-11 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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3F75
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![BU of 3f75 by Molmil](/molmil-images/mine/3f75) | Activated Toxoplasma gondii cathepsin L (TgCPL) in complex with its propeptide | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... | 著者 | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | 登録日 | 2008-11-07 | 公開日 | 2008-11-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl. J.Biol.Chem., 284, 2009
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4HWS
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![BU of 4hws by Molmil](/molmil-images/mine/4hws) | |
4HZC
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4DE0
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4DZW
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![BU of 4dzw by Molmil](/molmil-images/mine/4dzw) | Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | 著者 | Aripirala, S, Amzel, L.M, Gabelli, S.B. | 登録日 | 2012-03-01 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
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3D0R
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![BU of 3d0r by Molmil](/molmil-images/mine/3d0r) | Crystal structure of calG3 from Micromonospora echinospora determined in space group P2(1) | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Protein CalG3 | 著者 | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N. | 登録日 | 2008-05-02 | 公開日 | 2008-06-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chem.Biol., 15, 2008
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4DEF
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![BU of 4def by Molmil](/molmil-images/mine/4def) | Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis | 分子名称: | ACETATE ION, Fructose-bisphosphate aldolase, SODIUM ION, ... | 著者 | Capodagli, G.C, Pegan, S.D. | 登録日 | 2012-01-20 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis. Biochemistry, 52, 2013
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4E0L
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![BU of 4e0l by Molmil](/molmil-images/mine/4e0l) | FYLLYYT segment from human Beta 2 Microglobulin (62-68) displayed on 54-membered macrocycle scaffold | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide FYLLYYT(ORN)KN(HAO)SA(ORN) | 著者 | Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. | 登録日 | 2012-03-04 | 公開日 | 2012-12-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates. Proc.Natl.Acad.Sci.USA, 109, 2012
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3RUU
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![BU of 3ruu by Molmil](/molmil-images/mine/3ruu) | FXR with SRC1 and GSK237 | 分子名称: | 6-(4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)-1H-indole-3-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1, ... | 著者 | Williams, S.P, Madauss, K.P. | 登録日 | 2011-05-05 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene. Bioorg.Med.Chem.Lett., 21, 2011
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3D2O
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4I59
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3CY3
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![BU of 3cy3 by Molmil](/molmil-images/mine/3cy3) | Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and the JNK inhibitor V | 分子名称: | (2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile, 1,2-ETHANEDIOL, Pimtide peptide, ... | 著者 | Filippakopoulos, P, Bullock, A, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-04-25 | 公開日 | 2008-07-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and the JNK inhibitor V. To be Published
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3RZI
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![BU of 3rzi by Molmil](/molmil-images/mine/3rzi) | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan | 分子名称: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Jiao, W, Jameson, G.B, Hutton, R.D, Parker, E.J. | 登録日 | 2011-05-11 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. J.Mol.Biol., 415, 2012
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4E3J
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4E3X
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![BU of 4e3x by Molmil](/molmil-images/mine/4e3x) | Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, ... | 著者 | Tanner, J.J, Pemberton, T.A. | 登録日 | 2012-03-10 | 公開日 | 2012-07-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Proline: Mother Nature's cryoprotectant applied to protein crystallography. Acta Crystallogr.,Sect.D, 68, 2012
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3RYB
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![BU of 3ryb by Molmil](/molmil-images/mine/3ryb) | Lactococcal OppA complexed with SLSQSLSQS | 分子名称: | Oligopeptide, Oligopeptide-binding protein oppA | 著者 | Berntsson, R.P.-A, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. | 登録日 | 2011-05-11 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA. J.Bacteriol., 193, 2011
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4I5H
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3D5R
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![BU of 3d5r by Molmil](/molmil-images/mine/3d5r) | Crystal Structure of Efb-C (N138A) / C3d Complex | 分子名称: | Complement C3, Fibrinogen-binding protein | 著者 | Geisbrecht, B.V. | 登録日 | 2008-05-16 | 公開日 | 2008-09-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17, 2008
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4DAY
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![BU of 4day by Molmil](/molmil-images/mine/4day) | |
3D5T
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2NOO
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![BU of 2noo by Molmil](/molmil-images/mine/2noo) | Crystal Structure of Mutant NikA | 分子名称: | IODIDE ION, NICKEL (II) ION, Nickel-binding periplasmic protein | 著者 | Addy, C, Ohara, M, Kawai, F, Kidera, A, Ikeguchi, M, Fuchigami, S, Osawa, M, Shimada, I, Park, S.Y, Tame, J.R.H, Heddle, J.G. | 登録日 | 2006-10-26 | 公開日 | 2007-01-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Nickel binding to NikA: an additional binding site reconciles spectroscopy, calorimetry and crystallography. Acta Crystallogr.,Sect.D, 63, 2007
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3S5Z
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![BU of 3s5z by Molmil](/molmil-images/mine/3s5z) | Pharmacological Chaperoning in Human alpha-Galactosidase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ... | 著者 | Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2011-05-23 | 公開日 | 2012-01-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | The molecular basis of pharmacological chaperoning in human alpha-galactosidase Chem.Biol., 18, 2011
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