PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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3F5H	Crystal structure of fused docking domains from PikAIII and PikAIV of the pikromycin polyketide synthase 分子名称: SODIUM ION, Type I polyketide synthase PikAIII, Type I polyketide synthase PikAIV fusion protein 著者 Buchholz, T.J, Geders, T.W, Bartley, F.E, Reynolds, K.A, Smith, J.L, Sherman, D.H. 登録日 2008-11-03 公開日 2009-01-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. Acs Chem.Biol., 4, 2009
4D98	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group H32 at pH 7.5 分子名称: CHLORIDE ION, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ... 著者 Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4D9H	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with adenosine 分子名称: ADENOSINE, Purine nucleoside phosphorylase deoD-type 著者 Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. 登録日 2012-01-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
3F75	Activated Toxoplasma gondii cathepsin L (TgCPL) in complex with its propeptide 分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... 著者 Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) 登録日 2008-11-07 公開日 2008-11-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl. J.Biol.Chem., 284, 2009
4HWS	Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor 分子名称: N-{[3-(4-amino-2-chloroquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION 著者 Hilgers, M.T. 登録日 2012-11-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J.Med.Chem., 56, 2013
4HZC	Crystal structure of Serine acetyltransferase from Brucella abortus strain S19 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CysE, ... 著者 Kumar, S, Samudrala, G. 登録日 2012-11-15 公開日 2014-02-19 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Crystal structure of serine acetyl transferase from Brucella abortus and its complex with coenzyme A. Biochim.Biophys.Acta, 1844, 2014
4DE0	CTX-M-9 class A beta-lactamase complexed with compound 16 分子名称: Beta-lactamase, DIMETHYL SULFOXIDE, N-[3-(1H-tetrazol-5-yl)phenyl]-1H-benzimidazole-7-carboxamide 著者 Nichols, D.N, Chen, Y. 登録日 2012-01-19 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase J.Med.Chem., 55, 2012
4DZW	Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... 著者 Aripirala, S, Amzel, L.M, Gabelli, S.B. 登録日 2012-03-01 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
3D0R	Crystal structure of calG3 from Micromonospora echinospora determined in space group P2(1) 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Protein CalG3 著者 Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N. 登録日 2008-05-02 公開日 2008-06-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chem.Biol., 15, 2008
4DEF	Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis 分子名称: ACETATE ION, Fructose-bisphosphate aldolase, SODIUM ION, ... 著者 Capodagli, G.C, Pegan, S.D. 登録日 2012-01-20 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis. Biochemistry, 52, 2013
4E0L	FYLLYYT segment from human Beta 2 Microglobulin (62-68) displayed on 54-membered macrocycle scaffold 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide FYLLYYT(ORN)KN(HAO)SA(ORN) 著者 Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. 登録日 2012-03-04 公開日 2012-12-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates. Proc.Natl.Acad.Sci.USA, 109, 2012
3RUU	FXR with SRC1 and GSK237 分子名称: 6-(4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)-1H-indole-3-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1, ... 著者 Williams, S.P, Madauss, K.P. 登録日 2011-05-05 公開日 2011-09-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene. Bioorg.Med.Chem.Lett., 21, 2011
3D2O	Crystal Structure of Manganese-metallated GTP Cyclohydrolase Type IB 分子名称: AZIDE ION, CHLORIDE ION, LITHIUM ION, ... 著者 Swairjo, M.A. 登録日 2008-05-08 公開日 2009-05-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Zinc-independent folate biosynthesis: genetic, biochemical, and structural investigations reveal new metal dependence for GTP cyclohydrolase IB J.Bacteriol., 191, 2009
4I59	Cyclohexylamine Oxidase from Brevibacterium oxydans IH-35A complexed with cyclohexanone 分子名称: CYCLOHEXANONE, Cyclohexylamine Oxidase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Mirza, I.A, Berghuis, A.M. 登録日 2012-11-28 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Structural Analysis of a Novel Cyclohexylamine Oxidase from Brevibacterium oxydans IH-35A. Plos One, 8, 2013
3CY3	Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and the JNK inhibitor V 分子名称: (2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile, 1,2-ETHANEDIOL, Pimtide peptide, ... 著者 Filippakopoulos, P, Bullock, A, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2008-04-25 公開日 2008-07-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and the JNK inhibitor V. To be Published
3RZI	The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan 分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Jiao, W, Jameson, G.B, Hutton, R.D, Parker, E.J. 登録日 2011-05-11 公開日 2012-01-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. J.Mol.Biol., 415, 2012
4E3J	Crystal structure of AmpC beta-lactamase in complex with a designed 4-tetrazolyl benzene sulfonamide boronic acid inhibitor 分子名称: Beta-lactamase, PHOSPHATE ION, [({[4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid 著者 Eidam, O, Shoichet, B.K. 登録日 2012-03-09 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7999 Å) 主引用文献 Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3X	Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, ... 著者 Tanner, J.J, Pemberton, T.A. 登録日 2012-03-10 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Proline: Mother Nature's cryoprotectant applied to protein crystallography. Acta Crystallogr.,Sect.D, 68, 2012
3RYB	Lactococcal OppA complexed with SLSQSLSQS 分子名称: Oligopeptide, Oligopeptide-binding protein oppA 著者 Berntsson, R.P.-A, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. 登録日 2011-05-11 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA. J.Bacteriol., 193, 2011
4I5H	Crystal Structure of a Double Mutant Rat Erk2 Complexed With a Type II Quinazoline Inhibitor 分子名称: Mitogen-activated protein kinase 1, N-{3-[2-(cyclopropylamino)quinazolin-6-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide 著者 Hari, S.B, Maly, D.J, Merritt, E.A. 登録日 2012-11-28 公開日 2013-07-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Sequence determinants of a specific inactive protein kinase conformation. Chem.Biol., 20, 2013
3D5R	Crystal Structure of Efb-C (N138A) / C3d Complex 分子名称: Complement C3, Fibrinogen-binding protein 著者 Geisbrecht, B.V. 登録日 2008-05-16 公開日 2008-09-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17, 2008
4DAY	Crystal structure of the RMI core complex with MM2 peptide from FANCM 分子名称: Fanconi anemia group M protein, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 著者 Hoadley, K.A, Keck, J.L. 登録日 2012-01-13 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome. Proc.Natl.Acad.Sci.USA, 109, 2012
3D5T	Crystal structure of malate dehydrogenase from Burkholderia pseudomallei 分子名称: MAGNESIUM ION, Malate dehydrogenase, SODIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2008-05-16 公開日 2008-06-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Crystal Structure of Malate Dehydrogenase from Burkholderia pseudomallei. To be Published
2NOO	Crystal Structure of Mutant NikA 分子名称: IODIDE ION, NICKEL (II) ION, Nickel-binding periplasmic protein 著者 Addy, C, Ohara, M, Kawai, F, Kidera, A, Ikeguchi, M, Fuchigami, S, Osawa, M, Shimada, I, Park, S.Y, Tame, J.R.H, Heddle, J.G. 登録日 2006-10-26 公開日 2007-01-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Nickel binding to NikA: an additional binding site reconciles spectroscopy, calorimetry and crystallography. Acta Crystallogr.,Sect.D, 63, 2007
3S5Z	Pharmacological Chaperoning in Human alpha-Galactosidase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ... 著者 Guce, A.I, Clark, N.E, Garman, S.C. 登録日 2011-05-23 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 The molecular basis of pharmacological chaperoning in human alpha-galactosidase Chem.Biol., 18, 2011

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