3RZI
The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan
Summary for 3RZI
Entry DOI | 10.2210/pdb3rzi/pdb |
Related | 3KGF 3NUD 3NUE 3NV8 |
Descriptor | Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, PHENYLALANINE, ... (9 entities in total) |
Functional Keywords | dah7p synthase, shikimate pathway, aromatic biosynthesis, evolutionary relationships, transferase, phe+trp-bound, augmented tim-barrel structure, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, tim barrel |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 103631.09 |
Authors | Jiao, W.,Jameson, G.B.,Hutton, R.D.,Parker, E.J. (deposition date: 2011-05-11, release date: 2012-01-25, Last modification date: 2023-11-01) |
Primary citation | Jiao, W.,Hutton, R.D.,Cross, P.J.,Jameson, G.B.,Parker, E.J. Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. J.Mol.Biol., 415:716-726, 2012 Cited by PubMed: 22154807DOI: 10.1016/j.jmb.2011.11.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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