3RZI

The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis cocrystallized and complexed with phenylalanine and tryptophan

Summary for 3RZI

Entry DOI	10.2210/pdb3rzi/pdb
Related	3KGF 3NUD 3NUE 3NV8
Descriptor	Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, PHENYLALANINE, ... (9 entities in total)
Functional Keywords	dah7p synthase, shikimate pathway, aromatic biosynthesis, evolutionary relationships, transferase, phe+trp-bound, augmented tim-barrel structure, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, tim barrel
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	103631.09
Authors	Jiao, W.,Jameson, G.B.,Hutton, R.D.,Parker, E.J. (deposition date: 2011-05-11, release date: 2012-01-25, Last modification date: 2023-11-01)
Primary citation	Jiao, W.,Hutton, R.D.,Cross, P.J.,Jameson, G.B.,Parker, E.J. Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. J.Mol.Biol., 415:716-726, 2012 Cited by PubMed: 22154807 DOI: 10.1016/j.jmb.2011.11.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation