4DEF

Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis

Summary for 4DEF

Entry DOI	10.2210/pdb4def/pdb
Related	3EKL 3EKZ 3ELF 4DEL
Descriptor	Fructose-bisphosphate aldolase, ZINC ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	class ii fructose-1, 6-bisphosphate aldolase, zinc enzyme, dihydroxyacetone, glyceraldehyde-3-phosphate, aldol condensation, glycolysis, lyase, metal-binding
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	37488.96
Authors	Capodagli, G.C.,Pegan, S.D. (deposition date: 2012-01-20, release date: 2013-01-23, Last modification date: 2023-09-13)
Primary citation	Pegan, S.D.,Rukseree, K.,Capodagli, G.C.,Baker, E.A.,Krasnykh, O.,Franzblau, S.G.,Mesecar, A.D. Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis. Biochemistry, 52:912-925, 2013 Cited by PubMed: 23298222 DOI: 10.1021/bi300928u PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation