3D2O

Crystal Structure of Manganese-metallated GTP Cyclohydrolase Type IB

Summary for 3D2O

• Entry DOI: 10.2210/pdb3d2o/pdb
• Related: 3D1T
• Descriptor: UPF0343 protein NGO0387, MANGANESE (II) ION, LITHIUM ION, ... (6 entities in total)
• Functional Keywords: bimodular tunnel fold, tunneling fold, folate biosynthesis, gtp cyclohydrolase, metalloenzyme, manganese, hydrolase, biosynthetic protein
• Biological source: Neisseria gonorrhoeae
• Total number of polymer chains: 2
• Total formula weight: 57759.96

Authors

Swairjo, M.A. (deposition date: 2008-05-08, release date: 2009-05-12, Last modification date: 2023-08-30)

• Primary citation: Sankaran, B.,Bonnett, S.A.,Shah, K.,Gabriel, S.,Reddy, R.,Schimmel, P.,Rodionov, D.A.,de Crecy-Lagard, V.,Helmann, J.D.,Iwata-Reuyl, D.,Swairjo, M.A.; Zinc-independent folate biosynthesis: genetic, biochemical, and structural investigations reveal new metal dependence for GTP cyclohydrolase IB; J.Bacteriol., 191:6936-6949, 2009; PubMed: 19767425; DOI: 10.1128/JB.00287-09

Experimental method

X-RAY DIFFRACTION (2.04 Å)