3D5R
Crystal Structure of Efb-C (N138A) / C3d Complex
Summary for 3D5R
Entry DOI | 10.2210/pdb3d5r/pdb |
Related | 2GOM 2GOX 2NOJ 3D5S |
Descriptor | Complement C3, Fibrinogen-binding protein (3 entities in total) |
Functional Keywords | protein-protein complex, cell adhesion-toxin complex, site-directed mutation, age-related macular degeneration, cleavage on pair of basic residues, complement alternate pathway, complement pathway, disease mutation, glycoprotein, immune response, inflammatory response, innate immunity, phosphoprotein, polymorphism, secreted, thioester bond, cell adhesion/toxin |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01024 A6QG59 |
Total number of polymer chains | 4 |
Total formula weight | 81387.51 |
Authors | Geisbrecht, B.V. (deposition date: 2008-05-16, release date: 2008-09-09, Last modification date: 2023-08-30) |
Primary citation | Haspel, N.,Ricklin, D.,Geisbrecht, B.V.,Kavraki, L.E.,Lambris, J.D. Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17:1894-1906, 2008 Cited by PubMed: 18687868DOI: 10.1110/ps.036624.108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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