3D5R
Crystal Structure of Efb-C (N138A) / C3d Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Complement C3 | polymer | 297 | 33143.9 | 2 | UniProt (P01024) Pfam (PF07678) In PDB | Homo sapiens (human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
2 | C, D | Fibrinogen-binding protein | polymer | 65 | 7549.9 | 2 | UniProt (A6QG59) Pfam (PF12199) In PDB | Staphylococcus aureus subsp. aureus str. Newman | |
3 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 298 (UniProt: P01024)
C, D: 11 - 75 (UniProt: A6QG59)
PDB | External Database | Details |
---|---|---|
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Arg 4 | - | expression tag |
Ser 5 | - | expression tag |
Thr 6 | - | expression tag |
Ala 21 | Cys 1010 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 48 | Asn 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 81387.5 | |
All* | Total formula weight | 81387.5 |