PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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7FAH	Immune complex of head region of CA09 HA and neutralizing antibody 12H5 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Li, T.T, Xue, W.H, Gu, Y, Li, S.W. 登録日 2021-07-06 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.151 Å) 主引用文献 Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
7CR5	Complex structure of a human monoclonal antibody with SARS-CoV-2 nucleocapsid protein NTD 分子名称: Nucleoprotein, ZINC ION, monoclonal antibody chain H, ... 著者 Chen, S, Kang, S. 登録日 2020-08-12 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation. Nat Commun, 12, 2021
7CHO	Crystal structure of SARS-CoV-2 antibody P5A-1D2 with RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-1D2 heavy chain, ... 著者 Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. 登録日 2020-07-06 公開日 2021-05-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.561 Å) 主引用文献 Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
7CHS	Crystal structure of SARS-CoV-2 antibody P22A-1D1 with RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P22A-1D1 heavy chain, ... 著者 Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. 登録日 2020-07-06 公開日 2021-05-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
7CHP	Crystal structure of SARS-CoV-2 antibody P5A-3C8 with RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-3C8 heavy chain, ... 著者 Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. 登録日 2020-07-06 公開日 2021-05-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.357 Å) 主引用文献 Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
4KQ4	Crystal structure of Anti-IL-17A antibody CNTO7357 分子名称: CNTO7357 heavy chain, CNTO7357 light chain, NICKEL (II) ION 著者 Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. 登録日 2013-05-14 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
8DUL	Cryo-EM Structure of Antibody SKT05 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab SKT05 heavy chain, ... 著者 Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. 登録日 2022-07-27 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (4.17 Å) 主引用文献 Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186, 2023
8DUN	Cryo-EM Structure of Antibody SKW11 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody SKW11 heavy chain, ... 著者 Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. 登録日 2022-07-27 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (5.84 Å) 主引用文献 Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell, 186, 2023
7K45	SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2E12 neutralizing antibody Fab fragment (heavy chain), S2E12 neutralizing antibody Fab fragment (light chain), ... 著者 Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-09-14 公開日 2020-10-07 最終更新日 2023-10-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370, 2020
8TW3	hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein, Single domain antibody sdHMPV12, ... 著者 Rush, S.A, McLellan, J.S. 登録日 2023-08-19 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein. Mbio, 15, 2024
1CLO	ANTI-CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY A5B7 分子名称: A5B7 MONOCLONAL ANTIBODY 著者 Banfield, M.J, King, D.J, Mountain, A, Brady, R.L. 登録日 1996-05-01 公開日 1997-05-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs. Proteins, 29, 1997
4Q2Z	Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate 分子名称: Heavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody 著者 Navis, M, Tran, K, Bale, S, Phad, G, Guenaga, J, Wilson, R, Soldemo, M, McKee, K, Sundling, C, Mascola, J, Li, Y, Wyatt, R.T, Hedestam, G.B.K. 登録日 2014-04-10 公開日 2014-09-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization. Plos Pathog., 10, 2014
7RKS	Structure of the SARS-CoV receptor binding domain in complex with the human neutralizing antibody Fab fragment, C118 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Antibody Fab Heavy Chain, ... 著者 Jette, C.A, Bjorkman, P.J, Barnes, C.O. 登録日 2021-07-22 公開日 2021-09-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies. Cell Rep, 36, 2021
8SDF	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.4 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yuan, M, Wilson, I.A. 登録日 2023-04-06 公開日 2024-03-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift. Biorxiv, 2023
8HN6	Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD 分子名称: Heavy chain of monoclonal antibody 3G10, Light chain of monoclonal antibody 3G10, Spike protein S1 著者 Qi, J, Chen, Y. 登録日 2022-12-07 公開日 2023-05-17 最終更新日 2023-06-07 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents. Front Immunol, 14, 2023
8HN7	Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 3C11, Light chain of monoclonal antibody 3C11, ... 著者 Qi, J, Chen, Y. 登録日 2022-12-07 公開日 2023-05-17 最終更新日 2023-06-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents. Front Immunol, 14, 2023
8SDG	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.43 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralizing antibody CC25.43 heavy chain, Neutralizing antibody CC25.43 light chain, ... 著者 Yuan, M, Wilson, I.A. 登録日 2023-04-06 公開日 2024-03-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift. Biorxiv, 2023
8EOO	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibodies WRAIR-2063 and WRAIR-2151 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... 著者 Jensen, J.L, Sankhala, R.S, Joyce, M.G. 登録日 2022-10-03 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity. J.Virol., 97, 2023
7CHY	Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26 分子名称: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26, light chain of antibody binding fragment of IgG26 著者 Lee, C.C, Wang, A.H.J, Kuo, W.C. 登録日 2020-07-06 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP. J.Mol.Biol., 433, 2020
7CHZ	Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A 分子名称: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26A, light chain of antibody binding fragment of IgG26A 著者 Lee, C.C, Wang, A.H.J, Kuo, W.C. 登録日 2020-07-06 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP. J.Mol.Biol., 433, 2020
6N1W	Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody DFPH-a.15 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DFPH-a.15 Light chain, ... 著者 Acharya, P, Kwong, P.D. 登録日 2018-11-12 公開日 2019-07-24 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
6OCD	Ricin A chain bound to VHH antibody V6D4 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ... 著者 Rudolph, M.J. 登録日 2019-03-22 公開日 2020-04-01 最終更新日 2020-10-14 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
6OBM	Ricin A chain bound to VHH antibody V6A7 分子名称: CHLORIDE ION, Ricin A chain, VHH antibody V6A7 著者 Rudolph, M.J. 登録日 2019-03-21 公開日 2020-04-01 最終更新日 2020-10-14 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
3K81	Structure of the central interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies 分子名称: MP18 RNA editing complex protein, Single strand antibody VHH domain 著者 Park, Y.-J, Hol, W. 登録日 2009-10-13 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies. J.Struct.Biol., 174, 2011
6OBO	Ricin A chain bound to VHH antibody V6A6 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... 著者 Rudolph, M.J. 登録日 2019-03-21 公開日 2020-04-01 最終更新日 2020-10-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020

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