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8GQE
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Crystal structure of the W285A mutant of UVR8 in complex with RUP2
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ultraviolet-B receptor UVR8, WD repeat-containing protein RUP2
著者Wang, Y.D, Wang, L.X, Guan, Z.Y, chang, H.F, Yin, P.
登録日2022-08-30
公開日2022-09-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献RUP2 facilitates UVR8 redimerization via two interfaces.
Plant Commun., 4, 2023
8H0N
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Crystal structure of the human METTL1-WDR4 complex
分子名称: tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4
著者Jin, X.H, Guan, Z.Y, Gong, Z, Zhang, D.L.
登録日2022-09-30
公開日2023-07-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1.
Cell Discov, 9, 2023
8H7G
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Cryo-EM structure of the human SAGA complex
分子名称: Ataxin-7, STAGA complex 65 subunit gamma, Splicing factor 3B subunit 3, ...
著者Huang, J, Zhang, Y.
登録日2022-10-20
公開日2022-12-14
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of human SAGA transcriptional coactivator complex.
Cell Discov, 8, 2022
8HMF
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head module state 2 of Tetrahymena IFT-A
分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ...
著者Ma, Y, Wu, J, Lei, M.
登録日2022-12-03
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
8HMD
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base module state 2 of Tetrahymena IFT-A
分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ...
著者Ma, Y, Wu, J, Lei, M.
登録日2022-12-03
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
8HME
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head module state 1 of Tetrahymena IFT-A
分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ...
著者Ma, Y, Wu, J, Lei, M.
登録日2022-12-03
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
8HMC
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base module state 1 of Tetrahymena IFT-A
分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ...
著者Ma, Y, Wu, J, Lei, M.
登録日2022-12-03
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
8HTI
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Human Consensus Olfactory Receptor OR52c in Complex with Octanoic Acid (OCA) and G Protein
分子名称: Consensus Olfactory Receptor OR52c, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Choi, C.W, Bae, J, Choi, H.-J, Kim, J.
登録日2022-12-21
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
8IRU
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Dopamine Receptor D4R-Gi-Rotigotine complex
分子名称: CHOLESTEROL, D(4) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E.
登録日2023-03-19
公開日2023-06-21
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
8I02
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Cryo-EM structure of the SIN3S complex from S. pombe
分子名称: Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ...
著者Wang, C, Guo, Z, Zhan, X.
登録日2023-01-10
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Two assembly modes for SIN3 histone deacetylase complexes.
Cell Discov, 9, 2023
8I03
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Cryo-EM structure of the SIN3L complex from S. pombe
分子名称: Chromatin modification-related protein png2, Histone deacetylase clr6, POTASSIUM ION, ...
著者Wang, C, Guo, Z, Zhan, X.
登録日2023-01-10
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Two assembly modes for SIN3 histone deacetylase complexes.
Cell Discov, 9, 2023
8IFG
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Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe
分子名称: Chromatin modification-related protein eaf3, Cph1, Cph2, ...
著者Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D.
登録日2023-02-17
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Class I histone deacetylase complex: Structure and functional correlates.
Proc Natl Acad Sci U S A, 120, 2023
8IEC
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Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine)
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ...
著者Shin, J, Park, J, Cho, Y.
登録日2023-02-15
公開日2024-02-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
4V8Z
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Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex
分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ...
著者Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W.
登録日2013-07-20
公開日2014-07-09
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
4MK0
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Crystal structure of G protein-coupled receptor kinase 2 in complex with a a rationally designed paroxetine derivative
分子名称: 5-{[(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-1H-isoindol-1-one, Beta-adrenergic receptor kinase 1, GLYCEROL, ...
著者Homan, K.T, Tesmer, J.J.G.
登録日2013-09-04
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog.
Mol.Pharmacol., 85, 2014
1K8K
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Crystal Structure of Arp2/3 Complex
分子名称: ACTIN-LIKE PROTEIN 2, ACTIN-LIKE PROTEIN 3, ARP2/3 COMPLEX 16 KDA SUBUNIT, ...
著者Robinson, R.C, Turbedsky, K, Kaiser, D.A, Higgs, H.N, Marchand, J.-B, Choe, S, Pollard, T.D.
登録日2001-10-24
公開日2001-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Arp2/3 Complex
Science, 294, 2001
8AUV
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Cryo-EM structure of the plant 40S subunit
分子名称: 18S rRNA, MAGNESIUM ION, POTASSIUM ION, ...
著者Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R.
登録日2022-08-25
公開日2023-06-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution.
Nat.Plants, 9, 2023
8B2L
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Cryo-EM structure of the plant 80S ribosome
分子名称: 18S rRNA, 25S rRNA, 30S ribosomal protein S15, ...
著者Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R.
登録日2022-09-14
公開日2023-08-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution.
Nat.Plants, 9, 2023
9AYF
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BU of 9ayf by Molmil
Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-07
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9BKJ
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Cholecystokinin 1 receptor (CCK1R) Y140A mutant, Gq chimera (mGsqi) complex
分子名称: AMINO GROUP, Cholecystokinin receptor type A, Cholecystokinin-8, ...
著者Cary, B.P, Harikumar, K.G, Zhao, P, Desai, A.J, Mobbs, J.M, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J.
登録日2024-04-29
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
To Be Published
9BKK
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Cholecystokinin 1 receptor (CCK1R) sterol 7M mutant, Gq chimera (mGsqi) complex
分子名称: Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Harikumar, K.G, Zhao, P, Cary, B.P, Xu, X, Desai, A.J, Mobbs, J.I, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J.
登録日2024-04-29
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
To Be Published
6YW6
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Cryo-EM structure of the ARP2/3 1B5CL isoform complex.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ARPC1B, Actin-related protein 2, ...
著者von Loeffelholz, O, Moores, C, Purkiss, A.
登録日2020-04-29
公開日2020-07-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms.
Biol Open, 9, 2020
6Z6L
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Cryo-EM structure of human CCDC124 bound to 80S ribosomes
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
登録日2020-05-28
公開日2020-07-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6YW7
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Cryo-EM structure of the ARP2/3 1A5C isoform complex.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ...
著者von Loeffelholz, O, Moores, C, Purkiss, A.
登録日2020-04-29
公開日2020-07-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms.
Biol Open, 9, 2020
4V88
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The structure of the eukaryotic ribosome at 3.0 A resolution.
分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ...
著者Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M.
登録日2011-10-11
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the eukaryotic ribosome at 3.0 angstrom resolution.
Science, 334, 2011

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件を2024-06-26に公開中

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