8IEC
Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine)
Summary for 8IEC
Entry DOI | 10.2210/pdb8iec/pdb |
EMDB information | 35378 |
Descriptor | Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Single-chain variable fragment scFv16, ... (4 entities in total) |
Functional Keywords | membrane protein, g-protein coupled receptor, signal transduction, phospholipid, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 100683.46 |
Authors | |
Primary citation | Shin, J.,Park, J.,Jeong, J.,Lam, J.H.,Qiu, X.,Wu, D.,Kim, K.,Lee, J.Y.,Robinson, C.V.,Hyun, J.,Katritch, V.,Kim, K.P.,Cho, Y. Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31:678-687, 2024 Cited by PubMed: 38332368DOI: 10.1038/s41594-024-01224-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.18 Å) |
Structure validation
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