8IEC

Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine)

Summary for 8IEC

Entry DOI	10.2210/pdb8iec/pdb
EMDB information	35378
Descriptor	Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Single-chain variable fragment scFv16, ... (4 entities in total)
Functional Keywords	membrane protein, g-protein coupled receptor, signal transduction, phospholipid, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	100683.46
Authors	Shin, J.,Park, J.,Cho, Y. (deposition date: 2023-02-15, release date: 2024-02-14, Last modification date: 2024-02-21)
Primary citation	Shin, J.,Park, J.,Jeong, J.,Lam, J.H.,Qiu, X.,Wu, D.,Kim, K.,Lee, J.Y.,Robinson, C.V.,Hyun, J.,Katritch, V.,Kim, K.P.,Cho, Y. Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38332368 DOI: 10.1038/s41594-024-01224-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.18 Å)

Structure validation