PDB: 1466 件ウェブページステータス検索Chemie searchBIRD

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6FYX	Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... 著者 Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. 登録日 2018-03-12 公開日 2018-12-05 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
6FYY	Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... 著者 Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. 登録日 2018-03-12 公開日 2018-12-05 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
6FYH	Disulfide between ubiquitin G76C and the E3 HECT ligase Huwe1 分子名称: E3 ubiquitin-protein ligase HUWE1, Polyubiquitin-B, SULFATE ION, ... 著者 Jaeckl, M, Hartmann, M.D, Wiesner, S. 登録日 2018-03-12 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.906 Å) 主引用文献 beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation. J. Mol. Biol., 430, 2018
6FX4	Disulfide between E3 HECT ligase Smurf2 and Ubiquitin G76C 分子名称: E3 ubiquitin-protein ligase SMURF2, GLYCEROL, Polyubiquitin-B 著者 Jaeckl, M, Holdermann, I, Wiesner, S. 登録日 2018-03-08 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation. J. Mol. Biol., 430, 2018
5ZEW	A ubiquitin-like protein from the hyperthermophilic archaea Caldiarchaeum subterraneum 分子名称: Ubiquitin-like protein 著者 Mi, J, Ye, K.Q. 登録日 2018-02-28 公開日 2019-02-27 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 The hydrophobic effect and electrostatic interactions contribute to the thermostability of the ubiquitin-like protein from the hyperthermophilic archaea Caldiarchaeum subterraneum To Be Published
6FTX	Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin-remodeling ATPase, ... 著者 Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. 登録日 2018-02-25 公開日 2018-08-08 最終更新日 2018-10-17 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
5ZD0	Solution structure of human ubiquitin with three alanine mutations in living eukaryotic cells by in-cell NMR spectroscopy 分子名称: ubiquitin 著者 Tanaka, T, Ikeya, T, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y. 登録日 2018-02-22 公開日 2019-08-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells. Angew.Chem.Int.Ed.Engl., 58, 2019
6CFP	CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE 分子名称: 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, Ubiquitin-like protein SMT3,Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-15 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE To Be Published
5ZBU	Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub 分子名称: E3 ubiquitin-protein ligase RNF13, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Datta, A.B, Sarkar, S. 登録日 2018-02-12 公開日 2019-02-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub To Be Published
5ZBI	Crystal structure of asparaginyl endopeptidases from Viola Canadensis 分子名称: Peptide asparaginyl ligase, SODIUM ION 著者 Wong, Y.H, Lescar, J. 登録日 2018-02-12 公開日 2018-05-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structure of Peptide asparaginyl ligase from Viola canadensis To Be Published
6FNO	Caldiarchaeum Subterraneum Ubiquitin:Rpn11-homolog complex, zinc soak 分子名称: 26S proteasome regulatory subunit N11-like protein, SULFATE ION, Ubiquitin-like protein, ... 著者 Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. 登録日 2018-02-04 公開日 2018-07-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system. Nat Commun, 9, 2018
6FNN	Caldiarchaeum Subterraneum Ubiquitin:Rpn11-homolog complex 分子名称: 26S proteasome regulatory subunit N11-like protein, SULFATE ION, Ubiquitin-like protein, ... 著者 Fuchs, A.C.D, Albrecht, R, Martin, J, Hartmann, M.D. 登録日 2018-02-04 公開日 2018-07-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system. Nat Commun, 9, 2018
6FMI	pVHL:EloB:EloC in complex with N-((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamothioyl) pyrrolidin-1-yl)-1-oxopropan-2-yl)acetamide (ligand 2) 分子名称: Elongin-B, Elongin-C, von Hippel-Lindau disease tumor suppressor, ... 著者 Soares, P, Lucas, X, Ciulli, A. 登録日 2018-01-31 公開日 2018-04-11 最終更新日 2018-06-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Thioamide substitution to probe the hydroxyproline recognition of VHL ligands. Bioorg. Med. Chem., 26, 2018
6FMJ	pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-Acetamidopropanethioyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl) benzyl)pyrrolidine-2-carboxamide (ligand 3) 分子名称: (2~{S},4~{R})-1-[(2~{S})-2-acetamidopropanethioyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... 著者 Soares, P, Lucas, X, Ciulli, A. 登録日 2018-01-31 公開日 2018-04-11 最終更新日 2018-06-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Thioamide substitution to probe the hydroxyproline recognition of VHL ligands. Bioorg. Med. Chem., 26, 2018
6FMK	pVHL:EloB:EloC in complex with N-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamothioyl) pyrrolidin-1-yl)-1-thioxopropan-2-yl)acetamide (ligand 4) 分子名称: Elongin-B, Elongin-C, von Hippel-Lindau disease tumor suppressor, ... 著者 Soares, P, Lucas, X, Ciulli, A. 登録日 2018-01-31 公開日 2018-04-11 最終更新日 2018-06-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Thioamide substitution to probe the hydroxyproline recognition of VHL ligands. Bioorg. Med. Chem., 26, 2018
6FJ7	Caldiarchaeum Subterraneum Ubiquitin 分子名称: SULFATE ION, Ubiquitin-like protein 著者 Wojtynek, M, Martin, J, Hartmann, M.D. 登録日 2018-01-21 公開日 2018-07-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Rpn11-mediated ubiquitin processing in an ancestral archaeal ubiquitination system. Nat Commun, 9, 2018
6C5X	Crystal Structure of SOCS1 in complex with ElonginB and ElonginC 分子名称: Elongin-B, Elongin-C, GP130 peptide fragment, ... 著者 Kershaw, N.J, Laktyushin, A, Babon, J.J. 登録日 2018-01-17 公開日 2018-05-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.105 Å) 主引用文献 The molecular basis of JAK/STAT inhibition by SOCS1. Nat Commun, 9, 2018
5Z58	Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
5Z56	cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
5Z57	Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
6FGE	Crystal structure of human ZUFSP/ZUP1 in complex with ubiquitin 分子名称: ACETATE ION, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Kwasna, D, Abdul Rehman, S.A, Kulathu, Y. 登録日 2018-01-10 公開日 2018-04-04 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability. Mol. Cell, 70, 2018
6FFA	FMDV Leader protease bound to substrate ISG15 分子名称: GLYCEROL, Lbpro, SULFATE ION, ... 著者 Swatek, K.N, Pruneda, J.N, Komander, D. 登録日 2018-01-05 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C16	Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex. 分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1 著者 Manczyk, N, Sicheri, F. 登録日 2018-01-04 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure, 26, 2018
6FF7	human Bact spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... 著者 Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. 登録日 2018-01-03 公開日 2019-03-13 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
6FDK	Structure of Chlamydia trachomatis effector protein Cdu1 bound to ubiquitin 分子名称: CHLORIDE ION, Deubiquitinase and deneddylase Dub1, Polyubiquitin-B, ... 著者 Ramirez, Y, Kisker, C. 登録日 2017-12-25 公開日 2018-08-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis. ChemMedChem, 13, 2018

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