6FX4
Disulfide between E3 HECT ligase Smurf2 and Ubiquitin G76C
Summary for 6FX4
Entry DOI | 10.2210/pdb6fx4/pdb |
Descriptor | E3 ubiquitin-protein ligase SMURF2, Polyubiquitin-B, GLYCEROL, ... (4 entities in total) |
Functional Keywords | e3 hect ligase, ubiquitin transfer, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 45319.67 |
Authors | Jaeckl, M.,Holdermann, I.,Wiesner, S. (deposition date: 2018-03-08, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Jackl, M.,Stollmaier, C.,Strohaker, T.,Hyz, K.,Maspero, E.,Polo, S.,Wiesner, S. beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation. J. Mol. Biol., 430:3218-3233, 2018 Cited by PubMed: 29964046DOI: 10.1016/j.jmb.2018.06.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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