6FGE

Crystal structure of human ZUFSP/ZUP1 in complex with ubiquitin

Summary for 6FGE

• Entry DOI: 10.2210/pdb6fge/pdb
• Descriptor: Zinc finger with UFM1-specific peptidase domain protein, Polyubiquitin-B, MALONATE ION, ... (10 entities in total)
• Functional Keywords: hydrolase, cysteine protease, isopeptidase and ubiquitin binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Ubiquitin: Cytoplasm : P0CG47
• Total number of polymer chains: 2
• Total formula weight: 49377.14

Authors

Kwasna, D.,Abdul Rehman, S.A.,Kulathu, Y. (deposition date: 2018-01-10, release date: 2018-04-04, Last modification date: 2018-04-18)

• Primary citation: Kwasna, D.,Abdul Rehman, S.A.,Natarajan, J.,Matthews, S.,Madden, R.,De Cesare, V.,Weidlich, S.,Virdee, S.,Ahel, I.,Gibbs-Seymour, I.,Kulathu, Y.; Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.; Mol. Cell, 70:150-164.e6, 2018; PubMed: 29576527; DOI: 10.1016/j.molcel.2018.02.023

Experimental method

X-RAY DIFFRACTION (1.74 Å)