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2GM3
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BU of 2gm3 by Molmil
Crystal Structure of an Universal Stress Protein Family Protein from Arabidopsis Thaliana At3g01520 with AMP Bound
分子名称: ADENOSINE MONOPHOSPHATE, unknown protein
著者Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-04-05
公開日2006-04-18
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.461 Å)
主引用文献Crystal structure of the protein At3g01520, a eukaryotic universal stress protein-like protein from arabidopsis thaliana in complex with AMP.
Proteins, 83, 2015
5CHV
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BU of 5chv by Molmil
Crystal structure of USP18-ISG15 complex
分子名称: CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ...
著者Fritz, G, Basters, A.
登録日2015-07-10
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
5CHT
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BU of 5cht by Molmil
Crystal structure of USP18
分子名称: Ubl carboxyl-terminal hydrolase 18, ZINC ION
著者Fritz, G, Basters, A.
登録日2015-07-10
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
2HD5
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BU of 2hd5 by Molmil
USP2 in complex with ubiquitin
分子名称: Polyubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION
著者Renatus, M, Kroemer, M.
登録日2006-06-20
公開日2006-08-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2.
Structure, 14, 2006
5NGE
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BU of 5nge by Molmil
Crystal structure of USP7 in complex with the non-covalent inhibitor, FT671
分子名称: 5-[[1-[(3~{S})-4,4-bis(fluoranyl)-3-(3-fluoranylpyrazol-1-yl)butanoyl]-4-oxidanyl-piperidin-4-yl]methyl]-1-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-4-one, Ubiquitin carboxyl-terminal hydrolase 7
著者Turnbull, A.P, Krajewski, W.W, Ioannidis, S, Kessler, B.M, Komander, D.
登録日2017-03-17
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Nature, 550, 2017
5NGF
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BU of 5ngf by Molmil
Crystal structure of USP7 in complex with the covalent inhibitor, FT827
分子名称: 1,2-ETHANEDIOL, Ubiquitin carboxyl-terminal hydrolase 7, ~{N}-[2-[4-[4-[(1-methyl-4-oxidanylidene-pyrazolo[3,4-d]pyrimidin-5-yl)methyl]-4-oxidanyl-piperidin-1-yl]carbonylphenyl]phenyl]ethanesulfonamide
著者Krajewski, W.W, Turnbull, A.P, Ioannidis, S, Kessler, B.M, Komander, D.
登録日2017-03-17
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Nature, 550, 2017
5VS6
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BU of 5vs6 by Molmil
Structure of DUB complex
分子名称: ACETATE ION, GLYCEROL, N-[3-({4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl}methyl)-4-oxo-3,4-dihydroquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide, ...
著者Seo, H.-S, Dhe-Paganon, S.
登録日2017-05-11
公開日2017-12-20
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
5VSK
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BU of 5vsk by Molmil
Structure of DUB complex
分子名称: 7-chloro-3-({4-hydroxy-1-[(3S)-3-phenylbutanoyl]piperidin-4-yl}methyl)quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION
著者Seo, H.-Y, Dhe-Paganon, S.
登録日2017-05-11
公開日2017-12-20
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
5VSB
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BU of 5vsb by Molmil
Structure of DUB complex
分子名称: 7-chloro-3-{[4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl]methyl}quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7
著者Seo, H.-S, Dhe-Paganon, S.
登録日2017-05-11
公開日2017-12-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
5WCH
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BU of 5wch by Molmil
Crystal structure of the catalytic domain of human USP9X
分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X, UNKNOWN ATOM OR ION, ZINC ION
著者Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2017-06-30
公開日2018-07-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5K1A
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BU of 5k1a by Molmil
Crystal structure of the UAF1-USP12 complex in C2 space group
分子名称: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, ZINC ION
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-18
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5K1C
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BU of 5k1c by Molmil
Crystal structure of the UAF1/WDR20/USP12 complex
分子名称: PHOSPHATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Ubiquitin carboxyl-terminal hydrolase 12, ...
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-18
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5K16
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BU of 5k16 by Molmil
Crystal structure of free Ubiquitin-specific protease 12
分子名称: GLYCEROL, Ubiquitin carboxyl-terminal hydrolase 12, ZINC ION
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-17
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5K1B
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BU of 5k1b by Molmil
Crystal structure of the UAF1/USP12 complex in F222 space group
分子名称: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, ZINC ION
著者Li, H, D'Andrea, A.D, Zheng, N.
登録日2016-05-18
公開日2016-07-20
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
Mol.Cell, 63, 2016
5GVI
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BU of 5gvi by Molmil
Zebrafish USP30 in complex with Lys6-linked diubiquitin
分子名称: Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, ubiquitin
著者Sato, Y, Fukai, S.
登録日2016-09-05
公開日2017-09-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30
Nat. Struct. Mol. Biol., 24, 2017
4MSX
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BU of 4msx by Molmil
Crystal structure of an essential yeast splicing factor
分子名称: ACETATE ION, Pre-mRNA-splicing factor SAD1, ZINC ION
著者Hadjivassiliou, H, Guthrie, C, Rosenberg, O.S.
登録日2013-09-18
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing.
Rna, 20, 2014
5QYE
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BU of 5qye by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry E12a
分子名称: (2R)-6-amino-3-methyl-2,3-dihydro-1,3-benzoxazol-2-ol, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ...
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
8OYP
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BU of 8oyp by Molmil
Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic
分子名称: CADMIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I.
登録日2023-05-05
公開日2023-10-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity.
J.Biol.Chem., 299, 2023
5CVL
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BU of 5cvl by Molmil
WDR48 (UAF-1), residues 2-580
分子名称: GOLD ION, PHOSPHATE ION, WD repeat-containing protein 48
著者HARRIS, S.F, YIN, J.
登録日2015-07-27
公開日2015-10-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
6KAC
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BU of 6kac by Molmil
Cryo-EM structure of the C2S2-type PSII-LHCII supercomplex from Chlamydomonas reihardtii
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
著者Sheng, X, Li, A.J, Song, D.F, Liu, Z.F.
登録日2019-06-21
公開日2019-10-23
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural insight into light harvesting for photosystem II in green algae.
Nat.Plants, 5, 2019
8SY2
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BU of 8sy2 by Molmil
Peanut USP-type BURP Domain Peptide Cyclase
分子名称: BURP domain-containing protein
著者Mydy, L.S, Kersten, R.D, Smith, J.L.
登録日2023-05-24
公開日2024-02-14
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献An intramolecular macrocyclase in plant ribosomal peptide biosynthesis.
Nat.Chem.Biol., 20, 2024
8SY3
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BU of 8sy3 by Molmil
Copper Complex of Peanut USP-type BURP Domain Peptide Cyclase
分子名称: BURP domain-containing protein, COPPER (II) ION
著者Mydy, L.S, Kersten, R.D, Smith, J.L.
登録日2023-05-24
公開日2024-02-14
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献An intramolecular macrocyclase in plant ribosomal peptide biosynthesis.
Nat.Chem.Biol., 20, 2024
3QTB
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BU of 3qtb by Molmil
Structure of the universal stress protein from Archaeoglobus fulgidus in complex with dAMP
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ACETATE ION, Uncharacterized protein
著者Tkaczuk, K.L, Shumilin, I.A, Chruszcz, M, Cymborowski, M, Xu, X, Di Leo, R, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2011-02-22
公開日2011-03-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and functional insight into the universal stress protein family.
Evol Appl, 6, 2013
4W4U
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BU of 4w4u by Molmil
Structure of yeast SAGA DUBm with Sgf73 Y57A mutant at 2.8 angstroms resolution
分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ...
著者Wolberger, C, Yan, M.
登録日2014-08-15
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.
J.Mol.Biol., 427, 2015
2GFO
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BU of 2gfo by Molmil
Structure of the Catalytic Domain of Human Ubiquitin Carboxyl-terminal Hydrolase 8
分子名称: Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-03-22
公開日2006-04-04
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006

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