5K1C

Crystal structure of the UAF1/WDR20/USP12 complex

Summary for 5K1C

• Entry DOI: 10.2210/pdb5k1c/pdb
• Related: 5K16 5K19 5K1A 5K1B
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, WD repeat-containing protein 20, ... (7 entities in total)
• Functional Keywords: wd40 repeat domain, wdr20, usp12, uaf1, wdr48, deubiquitinating enzyme, ubiquitin-specific protease, usp1-associated factor 1, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q8TAF3
• Total number of polymer chains: 3
• Total formula weight: 167782.85

Authors

Li, H.,D'Andrea, A.D.,Zheng, N. (deposition date: 2016-05-18, release date: 2016-07-20, Last modification date: 2023-09-27)

• Primary citation: Li, H.,Lim, K.S.,Kim, H.,Hinds, T.R.,Jo, U.,Mao, H.,Weller, C.E.,Sun, J.,Chatterjee, C.,D'Andrea, A.D.,Zheng, N.; Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.; Mol.Cell, 63:249-260, 2016; PubMed: 27373336; DOI: 10.1016/j.molcel.2016.05.031

Experimental method

X-RAY DIFFRACTION (3 Å)