5K1B

Crystal structure of the UAF1/USP12 complex in F222 space group

Summary for 5K1B

Entry DOI	10.2210/pdb5k1b/pdb
Related	5K16 5K19 5K1A 5K1C
Descriptor	WD repeat-containing protein 48, Ubiquitin carboxyl-terminal hydrolase 12, ZINC ION (3 entities in total)
Functional Keywords	wd40 domain, sumo-like domain, ubiquitin-specific protease 12, usp12, usp1-associated factor 1, deubiquitinating enzyme, dub, protein binding-hydrolase complex, protein binding/hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	118918.06
Authors	Li, H.,D'Andrea, A.D.,Zheng, N. (deposition date: 2016-05-18, release date: 2016-07-20, Last modification date: 2019-11-20)
Primary citation	Li, H.,Lim, K.S.,Kim, H.,Hinds, T.R.,Jo, U.,Mao, H.,Weller, C.E.,Sun, J.,Chatterjee, C.,D'Andrea, A.D.,Zheng, N. Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63:249-260, 2016 Cited by PubMed: 27373336 DOI: 10.1016/j.molcel.2016.05.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation