5K1A

Crystal structure of the UAF1-USP12 complex in C2 space group

Summary for 5K1A

• Entry DOI: 10.2210/pdb5k1a/pdb
• Related: 5K16 5K19 5K1B 5K1C
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, ZINC ION, ... (4 entities in total)
• Functional Keywords: wd40 domain, ubiquitin-specific protease 12, usp12, usp1-associated factor 1, usp1, deubiquitinating enzyme, dub, sumo-like domain, sld, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 459886.32

Authors

Li, H.,D'Andrea, A.D.,Zheng, N. (deposition date: 2016-05-18, release date: 2016-07-20, Last modification date: 2023-09-27)

• Primary citation: Li, H.,Lim, K.S.,Kim, H.,Hinds, T.R.,Jo, U.,Mao, H.,Weller, C.E.,Sun, J.,Chatterjee, C.,D'Andrea, A.D.,Zheng, N.; Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.; Mol.Cell, 63:249-260, 2016; PubMed: 27373336; DOI: 10.1016/j.molcel.2016.05.031

Experimental method

X-RAY DIFFRACTION (2.3 Å)