4MSX

Crystal structure of an essential yeast splicing factor

Summary for 4MSX

Entry DOI	10.2210/pdb4msx/pdb
Descriptor	Pre-mRNA-splicing factor SAD1, ZINC ION, ACETATE ION, ... (4 entities in total)
Functional Keywords	deubiquitinase, zinc finger ubiquitin binding protein, znf-ubp, ubiquitin specific protease, usp, pre-mrna splicing, spliceosome assembly, pseudo-deubiquitinase, nuclear, splicing
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Cellular location	Nucleus: P43589
Total number of polymer chains	1
Total formula weight	55986.00
Authors	Hadjivassiliou, H.,Guthrie, C.,Rosenberg, O.S. (deposition date: 2013-09-18, release date: 2014-04-16, Last modification date: 2024-02-28)
Primary citation	Hadjivassiliou, H.,Rosenberg, O.S.,Guthrie, C. The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. Rna, 20:656-669, 2014 Cited by PubMed: 24681967 DOI: 10.1261/rna.042838.113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation