4MSX

Crystal structure of an essential yeast splicing factor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000245	biological_process	spliceosomal complex assembly
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0004843	molecular_function	cysteine-type deubiquitinase activity
A	0005634	cellular_component	nucleus
A	0005681	cellular_component	spliceosomal complex
A	0006397	biological_process	mRNA processing
A	0008270	molecular_function	zinc ion binding
A	0008380	biological_process	RNA splicing
A	0016579	biological_process	protein deubiquitination
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0046872	molecular_function	metal ion binding
A	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	CYS60
A	CYS63
A	HIS79
A	HIS85

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 502

Chain	Residue
A	HOH909
A	ASN346
A	ARG347
A	ASP349
A	ASN360
A	HOH777

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	97
Details	ZN_FING: UBP-type; degenerate => ECO:0000255|PROSITE-ProRule:PRU00502

Chain	Residue	Details
A	PRO27-THR124

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00502

Chain	Residue	Details
A	CYS60
A	CYS63
A	HIS79
A	HIS85

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
A	MET1

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