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7V48
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Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8OQI
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BU of 8oqi by Molmil
Cryo-EM structure of the wild-type alpha-synuclein fibril.
分子名称: Alpha-synuclein
著者Pesch, V, Reithofer, S, Ma, L, Flores-Fernandez, J.M, Oezduezenciler, P, Busch, Y, Lien, Y, Rudtke, O, Frieg, B, Schroeder, G.F, Wille, H, Tamgueney, G.
登録日2023-04-12
公開日2024-03-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease.
Brain, 147, 2024
7NCJ
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BU of 7ncj by Molmil
Type 2AB alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1
分子名称: Alpha-synuclein
著者Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
登録日2021-01-28
公開日2021-02-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCG
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BU of 7ncg by Molmil
Type 2A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2
分子名称: Alpha-synuclein
著者Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
登録日2021-01-28
公開日2021-02-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCI
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BU of 7nci by Molmil
Type 2B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1
分子名称: Alpha-synuclein
著者Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
登録日2021-01-28
公開日2021-02-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCH
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BU of 7nch by Molmil
Type 1B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1
分子名称: Alpha-synuclein
著者Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
登録日2021-01-28
公開日2021-02-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCK
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BU of 7nck by Molmil
Type 3 alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 5
分子名称: Alpha-synuclein
著者Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
登録日2021-01-28
公開日2021-02-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCA
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BU of 7nca by Molmil
Type 1A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2
分子名称: Alpha-synuclein
著者Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
登録日2021-01-28
公開日2021-02-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7LC9
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BU of 7lc9 by Molmil
Cryo-EM structure of the N-terminal alpha-synuclein truncation 41-140
分子名称: Alpha-synuclein
著者Xiaodan, N, Ryan, P.M, Jiansen, J, Jennifer, C.L.
登録日2021-01-10
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The N terminus of alpha-synuclein dictates fibril formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
8RQM
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BU of 8rqm by Molmil
Alpha-synuclein amyloid fibrils
分子名称: Alpha-synuclein
著者Saibil, H.R, Monistrol, J.
登録日2024-01-18
公開日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly
Biorxiv, 2024
8RRR
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BU of 8rrr by Molmil
Alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Saibil, H.R, Monistrol, J.
登録日2024-01-23
公開日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly
Biorxiv, 2024
8PIX
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BU of 8pix by Molmil
Cryo EM structure of the type 3C polymorph of alpha-synuclein at low pH.
分子名称: Alpha-synuclein
著者Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R.
登録日2023-06-22
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Elife, 2023
8PK4
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BU of 8pk4 by Molmil
Cryo EM structure of the type 5A polymorph of alpha-synuclein.
分子名称: Alpha-synuclein
著者Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R.
登録日2023-06-24
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Elife, 2023
8PK2
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BU of 8pk2 by Molmil
Cryo EM structure of the type 1m polymorph of alpha-synuclein
分子名称: Alpha-synuclein
著者Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R.
登録日2023-06-24
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Elife, 2023
8PIC
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BU of 8pic by Molmil
Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH.
分子名称: Alpha-synuclein, CHLORIDE ION
著者Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R.
登録日2023-06-21
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Elife, 2023
8PJO
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BU of 8pjo by Molmil
Cryo EM structure of the type 3D polymorph of alpha-synuclein E46K mutant at low pH.
分子名称: Alpha-synuclein, CHLORIDE ION
著者Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R.
登録日2023-06-23
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Elife, 2023
8RI9
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BU of 8ri9 by Molmil
Late alpha-Synuclein fibril structure from liquid-liquid phase separations.
分子名称: Alpha-synuclein
著者De Simone, A, Barritt, J.D, Chen, S, Cascella, R, Cecchi, C, Bigi, A, Jarvis, J.A, Chiti, F, Dobson, C.M, Fusco, G.
登録日2023-12-18
公開日2024-03-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure-Toxicity Relationship in Intermediate Fibrils from alpha-Synuclein Condensates.
J.Am.Chem.Soc., 146, 2024
8CZ6
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BU of 8cz6 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYV
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BU of 8cyv by Molmil
CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYW
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BU of 8cyw by Molmil
CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYY
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BU of 8cyy by Molmil
CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYX
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BU of 8cyx by Molmil
CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CZ1
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BU of 8cz1 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYR
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BU of 8cyr by Molmil
Alpha-synuclein fibril from spontaneous control
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Distinct cryo-EM structures and functions of alpha-synuclein fibrils amplified from cerebrospinal fluid
To Be Published
8CYS
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BU of 8cys by Molmil
CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published

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