PDB: 108 件ウェブページステータス検索Chemie searchBIRD

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8OQI	Cryo-EM structure of the wild-type alpha-synuclein fibril. 分子名称: Alpha-synuclein 著者 Pesch, V, Reithofer, S, Ma, L, Flores-Fernandez, J.M, Oezduezenciler, P, Busch, Y, Lien, Y, Rudtke, O, Frieg, B, Schroeder, G.F, Wille, H, Tamgueney, G. 登録日 2023-04-12 公開日 2024-03-13 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease. Brain, 147, 2024
8PK2	Cryo EM structure of the type 1m polymorph of alpha-synuclein 分子名称: Alpha-synuclein 著者 Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. 登録日 2023-06-24 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
8PIX	Cryo EM structure of the type 3C polymorph of alpha-synuclein at low pH. 分子名称: Alpha-synuclein 著者 Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. 登録日 2023-06-22 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
8PIC	Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH. 分子名称: Alpha-synuclein, CHLORIDE ION 著者 Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. 登録日 2023-06-21 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.42 Å) 主引用文献 On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
8PJO	Cryo EM structure of the type 3D polymorph of alpha-synuclein E46K mutant at low pH. 分子名称: Alpha-synuclein, CHLORIDE ION 著者 Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. 登録日 2023-06-23 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.31 Å) 主引用文献 On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
8PK4	Cryo EM structure of the type 5A polymorph of alpha-synuclein. 分子名称: Alpha-synuclein 著者 Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. 登録日 2023-06-24 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
8RRR	Alpha-synuclein amyloid fibril 分子名称: Alpha-synuclein 著者 Saibil, H.R, Monistrol, J. 登録日 2024-01-23 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly Biorxiv, 2024
8RQM	Alpha-synuclein amyloid fibrils 分子名称: Alpha-synuclein 著者 Saibil, H.R, Monistrol, J. 登録日 2024-01-18 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Stepwise recruitment of Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibre disassembly Biorxiv, 2024
7UAK	Structure of recombinantly assembled A53E alpha-synuclein fibrils 分子名称: Alpha-synuclein 著者 Zhou, K, Zhou, H. 登録日 2022-03-13 公開日 2023-03-29 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Cryo-EM structure of amyloid fibril formed by alpha-synuclein hereditary A53E mutation reveals a distinct protofilament interface. J.Biol.Chem., 299, 2023
8CE7	Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein 分子名称: Alpha-synuclein 著者 Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. 登録日 2023-02-01 公開日 2023-03-01 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathol, 145, 2023
8CEB	Type2 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein 分子名称: Alpha-synuclein 著者 Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Sew, P.C, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. 登録日 2023-02-01 公開日 2023-03-08 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathol, 145, 2023
7V4B	Heparin-induced alpha-synuclein fibrils polymorph 3 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Sun, Y.P, Liu, C, Li, D. 登録日 2021-08-12 公開日 2022-08-17 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Heparin-induced alpha-synuclein fibrils polymorph 3 To Be Published
7V4C	Heparin-induced alpha-synuclein fibrils polymorph 4 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Sun, Y.P, Liu, C, Li, D. 登録日 2021-08-12 公開日 2022-08-17 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Heparin-induced alpha-synuclein fibrils polymorph 4 To Be Published
7V47	Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient 分子名称: Alpha-synuclein 著者 Fan, Y, Sun, Y.P, Wang, J, Liu, C. 登録日 2021-08-12 公開日 2022-08-17 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease. Structure, 31, 2023
7V48	Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient 分子名称: Alpha-synuclein 著者 Fan, Y, Sun, Y.P, Wang, J, Liu, C. 登録日 2021-08-12 公開日 2022-08-17 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease. Structure, 31, 2023
7V4A	Heparin-induced alpha-synuclein fibrils polymorph 1 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Sun, Y.P, Liu, C, Li, D. 登録日 2021-08-12 公開日 2022-08-17 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Heparin-induced alpha-synuclein fibrils polymorph 1 To Be Published
7V4D	Heparin-remodelled alpha-synuclein fibrils 分子名称: Alpha-synuclein 著者 Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D. 登録日 2021-08-12 公開日 2022-08-17 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Heparin-remodelled alpha-synuclein fibrils To Be Published
7V49	Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient 分子名称: Alpha-synuclein 著者 Fan, Y, Sun, Y.P, Wang, J, Liu, C. 登録日 2021-08-12 公開日 2022-08-17 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease. Structure, 31, 2023
7WO0	CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions 分子名称: Alpha-synuclein 著者 Wu, K.-P, Huang, J.Y.-C. 登録日 2022-01-20 公開日 2023-01-25 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Calcium abolishes intramolecular long-range contacts and promotes hereditary alpha-synuclein A53T aggregation To Be Published
8CYS	CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I 分子名称: Alpha-synuclein 著者 Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. 登録日 2022-05-24 公開日 2023-05-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
8CYV	CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II 分子名称: Alpha-synuclein 著者 Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. 登録日 2022-05-24 公開日 2023-05-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
7WMM	alpha-synuclein fibril-F0502B complex 分子名称: 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein 著者 Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. 登録日 2022-01-15 公開日 2023-01-18 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 alpha-synuclein fibril-F0502B complex To Be Published
8CZ2	CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII 分子名称: Alpha-synuclein 著者 Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. 登録日 2022-05-24 公開日 2023-05-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
8CZ6	CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X 分子名称: Alpha-synuclein 著者 Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. 登録日 2022-05-24 公開日 2023-05-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
8CYX	CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III 分子名称: Alpha-synuclein 著者 Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. 登録日 2022-05-24 公開日 2023-05-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published

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