8PJO
Cryo EM structure of the type 3D polymorph of alpha-synuclein E46K mutant at low pH.
Summary for 8PJO
| Entry DOI | 10.2210/pdb8pjo/pdb |
| Related | 8PIC 8PIX |
| EMDB information | 17714 |
| Descriptor | Alpha-synuclein, CHLORIDE ION (3 entities in total) |
| Functional Keywords | amyloid, polymorphism, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 10 |
| Total formula weight | 145116.28 |
| Authors | Frey, L.,Qureshi, B.M.,Kwiatkowski, W.,Rhyner, D.,Greenwald, J.,Riek, R. (deposition date: 2023-06-23, release date: 2024-05-29) |
| Primary citation | Frey, L.,Ghosh, D.,Qureshi, B.M.,Rhyner, D.,Pokharna, A.,Guerrero-Ferreira, R.,Kwiatkowski, W.,Serdiuk, T.,Picotti, P.,Riek, R.,Greenwald, J. On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023 Cited by DOI: 10.7554/eLife.93562.1PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.31 Å) |
Structure validation
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