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7WO0

CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions

Summary for 7WO0
Entry DOI10.2210/pdb7wo0/pdb
EMDB information32637
DescriptorAlpha-synuclein (1 entity in total)
Functional Keywordsprotein fibril
Biological sourceHomo sapiens (human)
Total number of polymer chains14
Total formula weight90542.05
Authors
Wu, K.-P.,Huang, J.Y.-C. (deposition date: 2022-01-20, release date: 2023-01-25, Last modification date: 2024-06-26)
Primary citationHuang, J.Y.-C.,Wu, K.-P.
Calcium abolishes intramolecular long-range contacts and promotes hereditary alpha-synuclein A53T aggregation
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.7 Å)
Structure validation

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