7WO0

CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions

Summary for 7WO0

Entry DOI	10.2210/pdb7wo0/pdb
EMDB information	32637
Descriptor	Alpha-synuclein (1 entity in total)
Functional Keywords	protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	14
Total formula weight	90542.05
Authors	Wu, K.-P.,Huang, J.Y.-C. (deposition date: 2022-01-20, release date: 2023-01-25)
Primary citation	Huang, J.Y.-C.,Wu, K.-P. Calcium abolishes intramolecular long-range contacts and promotes hereditary alpha-synuclein A53T aggregation To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation