8CZ2
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII
Summary for 8CZ2
Entry DOI | 10.2210/pdb8cz2/pdb |
EMDB information | 27082 27083 27084 27085 27086 27087 27088 27089 27090 27091 27092 27093 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | alpha-synuclein, cerebrospinal fluid (csf), protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 173713.30 |
Authors | Zhou, Y.,Sokratian, A.,Xu, E.,Viverette, E.,Dillard, L.,Yuan, Y.,Li, J.Y.,Matarangas, A.,Bouvette, J.,Borgnia, M.,Bartesaghi, A.,West, A. (deposition date: 2022-05-24, release date: 2023-05-31, Last modification date: 2024-06-12) |
Primary citation | Zhou, Y.,Sokratian, A.,Xu, E.,Viverette, E.,Dillard, L.,Yuan, Y.,Li, J.Y.,Matarangas, A.,Bouvette, J.,Borgnia, M.,Bartesaghi, A.,West, A. Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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