8PIX
Cryo EM structure of the type 3C polymorph of alpha-synuclein at low pH.
Summary for 8PIX
Entry DOI | 10.2210/pdb8pix/pdb |
Related | 8PIC |
EMDB information | 17693 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | amyloid, polymorphism, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 10 |
Total formula weight | 144761.08 |
Authors | Frey, L.,Qureshi, B.M.,Kwiatkowski, W.,Rhyner, D.,Greenwald, J.,Riek, R. (deposition date: 2023-06-22, release date: 2024-05-29) |
Primary citation | Frey, L.,Ghosh, D.,Qureshi, B.M.,Rhyner, D.,Pokharna, A.,Guerrero-Ferreira, R.,Kwiatkowski, W.,Serdiuk, T.,Picotti, P.,Riek, R.,Greenwald, J. On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023 Cited by DOI: 10.7554/eLife.93562.1PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.41 Å) |
Structure validation
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