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4U54
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-24
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
5HOO
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Crystal structure of the Mos1 Strand Transfer Complex
分子名称: MAGNESIUM ION, Mariner Mos1 transposase, Mos1 IR DNA NTS, ...
著者Richardson, J.M, Morris, E.R.
登録日2016-01-19
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A bend, flip and trap mechanism for transposon integration.
Elife, 5, 2016
4U7Y
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Structure of the complex of VPS4B MIT and IST1 MIM
分子名称: IST1 homolog, Vacuolar protein sorting-associated protein 4B
著者Guo, E.Z, Xu, Z.
登録日2014-07-31
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
4U2U
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Bak domain swapped dimer induced by BidBH3 with CHAPS
分子名称: Bcl-2 homologous antagonist/killer
著者Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2014-07-18
公開日2014-09-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers.
Mol.Cell, 55, 2014
4U5T
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Crystal Structure of VBP Leucine Zipper with Bound Arylstibonic Acid
分子名称: (2Z)-3-{3-[dihydroxy(oxido)-lambda~5~-stibanyl]phenyl}prop-2-enoic acid, VBP leucine zipper
著者Stagno, J.R, Ji, X.
登録日2014-07-25
公開日2014-08-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献P6981, an arylstibonic acid, is a novel low nanomolar inhibitor of cAMP response element-binding protein binding to DNA.
Mol.Pharmacol., 82, 2012
4U5U
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U58
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-24
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5O
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
7SB8
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d(GA(CGA)5) parallel-stranded homo-duplex
分子名称: COBALT HEXAMMINE(III), GA(CGA)5, SODIUM ION, ...
著者Luteran, E.M, Paukstelis, P.J.
登録日2021-09-24
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.317 Å)
主引用文献The parallel-stranded d(CGA) duplex is a highly predictable structural motif with two conformationally distinct strands.
Acta Crystallogr D Struct Biol, 78, 2022
4U7I
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Structure of the complex of Spartin MIT and IST1 MIM
分子名称: IST1 homolog, Spartin
著者Guo, E.Z, Xu, Z.
登録日2014-07-30
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
1B72
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PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX
分子名称: DNA (5'-D(*AP*CP*TP*CP*TP*AP*TP*GP*AP*TP*TP*GP*AP*TP*CP*GP*GP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*CP*CP*GP*AP*TP*CP*AP*AP*TP*CP*AP*TP*AP*GP*AP*G)-3'), PROTEIN (HOMEOBOX PROTEIN HOX-B1), ...
著者Piper, D.E, Batchelor, A.H, Chang, C.-P, Cleary, M.L, Wolberger, C.
登録日1999-01-27
公開日1999-02-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.
Cell(Cambridge,Mass.), 96, 1999
6ZMV
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BU of 6zmv by Molmil
Structure of muramidase from Trichobolus zukalii
分子名称: GLYCEROL, SULFATE ION, muramidase
著者Moroz, O.V, Blagova, E, Taylor, E, Turkenburg, J.P, Skov, L.K, Gippert, G.P, Schnorr, K.M, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Nymand-Grarup, S, Davies, G.J, Wilson, K.S.
登録日2020-07-04
公開日2021-07-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78 angstrom resolution.
Plos One, 16, 2021
4UJ6
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Structure of surface layer protein SbsC, domains 1-6
分子名称: SURFACE LAYER PROTEIN
著者Dordic, A, Pavkov-Keller, T, Eder, M, Egelseer, E.M, Davis, K, Mills, D, Sleytr, U.B, Kuehlbrandt, W, Vonck, J, Keller, W.
登録日2015-04-08
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of Surface Layer Protein Sbsc, Domains 1-6
To be Published
4X0Q
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BU of 4x0q by Molmil
Ternary complex of human DNA polymerase theta C-terminal domain binding ddGTP opposite dCMP
分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*TP*CP*AP*TP*TP*G)-3'), ...
著者Zahn, K.E, Doublie, S.
登録日2014-11-22
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Human DNA polymerase theta grasps the primer terminus to mediate DNA repair.
Nat.Struct.Mol.Biol., 22, 2015
4UHY
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Crystal structure of the human RGMA-BMP2 complex
分子名称: BONE MORPHOGENETIC PROTEIN 2, REPULSIVE GUIDANCE MOLECULE A
著者Healey, E.G, Bishop, B, Elegheert, J, Bell, C.H, Padilla-Parra, S, Siebold, C.
登録日2015-03-27
公開日2015-05-06
最終更新日2015-06-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein.
Nat.Struct.Mol.Biol., 22, 2015
4UCT
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BU of 4uct by Molmil
Fragment bound to H.influenza NAD dependent DNA ligase
分子名称: 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 2-amino-6-methyl-5-(propan-2-yloxy)-3H-[1,2,4]triazolo[1,5-a]pyrimidin-8-ium, DNA LIGASE
著者Hale, M, Brassington, C, Carcanague, D, Embrey, K, Eyermann, C.J, Giacobbe, R.A, Gingipali, L, Gowravaram, M, Harang, J, Howard, T, Ioannidis, G, Jahic, H, Kutschke, A, Laganas, V.A, Loch, J, Miller, M.D, Murphy-Benenato, K.E, Oguto, H, Otterbein, L, Patel, S.J, Shapiro, A.B, Boriack-Sjodin, P.A.
登録日2014-12-04
公開日2015-10-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献From Fragments to Leads: Novel Bacterial Nad+-Dependent DNA Ligase Inhibitors
Tetrahedron Lett., 56, 2015
8F9W
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Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein NPDP peptide
分子名称: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.8 Antibody, ...
著者Thai, E, Prieto, K, Julien, J.P.
登録日2022-11-24
公開日2023-11-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8F9V
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Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein KQPA peptide
分子名称: 1,2-ETHANEDIOL, Circumsporozoite protein KQPA peptide, Ky15.8 Antibody, ...
著者Thai, E, Prieto, K, Julien, J.P.
登録日2022-11-24
公開日2023-11-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
4UCV
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BU of 4ucv by Molmil
Fragment bound to H.influenza NAD dependent DNA ligase
分子名称: 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 8-methoxy-2,3-dimethylquinoxalin-5-ol, DNA LIGASE
著者Hale, M, Brassington, C, Carcanague, D, Embrey, K, Eyermann, C.J, Giacobbe, R.A, Gingipali, L, Gowravaram, M, Harang, J, Howard, T, Ioannidis, G, Jahic, H, Kutschke, A, Laganas, V.A, Loch, J, Miller, M.D, Murphy-Benenato, K.E, Oguto, H, Otterbein, L, Patel, S.J, Shapiro, A.B, Boriack-Sjodin, P.A.
登録日2014-12-04
公開日2015-10-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献From Fragments to Leads: Novel Bacterial Nad+-Dependent DNA Ligase Inhibitors
Tetrahedron Lett., 56, 2015
7OWE
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BU of 7owe by Molmil
Odinarchaeota Adenylate kinase (OdinAK) in complex with inhibitor Ap5a
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE
著者Grundstrom, C, Aberg-Zingmark, E, Verma, A, Wolf-Watz, M, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2021-06-18
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases.
Sci Adv, 8, 2022
7OWK
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Odinarchaeota Adenylate kinase (OdinAK) in complex with dTTP
分子名称: Adenylate kinase, THYMIDINE-5'-TRIPHOSPHATE
著者Aberg-Zingmark, E, Grundstrom, C, Verma, A, Wolf-Watz, M, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2021-06-18
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases.
Sci Adv, 8, 2022
8EK5
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Engineered scFv 10LH bound to PHOX2B/HLA-A24:02
分子名称: 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ...
著者Garfinkle, S.E, Florio, T.J, Sgourakis, N.G.
登録日2022-09-20
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sci Immunol, 8, 2023
7OWH
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Odinarchaeota Adenylate kinase (OdinAK) native structure
分子名称: Adenylate kinase, CHLORIDE ION
著者Aberg-Zingmark, E, Grundstrom, C, Verma, A, Wolf-Watz, M, Sauer, U.H, Sauer-Eriksson, A.E.
登録日2021-06-18
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases.
Sci Adv, 8, 2022
4UMV
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CRYSTAL STRUCTURE OF A ZINC-TRANSPORTING PIB-TYPE ATPASE IN THE E2P STATE
分子名称: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ZINC-TRANSPORTING ATPASE
著者Wang, K.T, Sitsel, O, Meloni, G, Autzen, H.E, Andersson, M, Klymchuk, T, Nielsen, A.M, Rees, D.C, Nissen, P, Gourdon, P.
登録日2014-05-21
公開日2014-08-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Mechanism of Zn(2+)-Transporting P-Type Atpases.
Nature, 514, 2014
7ND4
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EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-88 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-88 Fab heavy chain, ...
著者Duyvesteyn, H.M.E, Zhao, Y, Ren, J, Stuart, D.
登録日2021-01-30
公開日2021-03-03
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The antigenic anatomy of SARS-CoV-2 receptor binding domain.
Cell, 184, 2021

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