4U2U

Bak domain swapped dimer induced by BidBH3 with CHAPS

Summary for 4U2U

Related4U2V
DescriptorBcl-2 homologous antagonist/killer (2 entities in total)
Functional Keywordsapoptosis, bak, bcl-2
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight37960.54
Authors
Brouwer, J.M.,Colman, P.M.,Czabotar, P.E. (deposition date: 2014-07-18, release date: 2014-09-10, Last modification date: 2020-01-08)
Primary citation
Brouwer, J.M.,Westphal, D.,Dewson, G.,Robin, A.Y.,Uren, R.T.,Bartolo, R.,Thompson, G.V.,Colman, P.M.,Kluck, R.M.,Czabotar, P.E.
Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers.
Mol.Cell, 55:938-946, 2014
PubMed: 25175025 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2014.07.016
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.297203.8%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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