4UHY
Crystal structure of the human RGMA-BMP2 complex
Summary for 4UHY
Entry DOI | 10.2210/pdb4uhy/pdb |
Related | 4UHZ 4UI0 4UI1 4UI2 |
Descriptor | BONE MORPHOGENETIC PROTEIN 2, REPULSIVE GUIDANCE MOLECULE A (2 entities in total) |
Functional Keywords | signaling protein, bone morphogenetic protein pathway, hemojuvelin, morphogen, axon guidance, cell surface receptor signaling |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P12643 Cell membrane ; Lipid-anchor, GPI-anchor : Q96B86 |
Total number of polymer chains | 3 |
Total formula weight | 37476.54 |
Authors | Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. (deposition date: 2015-03-27, release date: 2015-05-06, Last modification date: 2015-06-17) |
Primary citation | Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein. Nat.Struct.Mol.Biol., 22:458-, 2015 Cited by PubMed: 25938661DOI: 10.1038/NSMB.3016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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