4UHY

Crystal structure of the human RGMA-BMP2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	BONE MORPHOGENETIC PROTEIN 2	polymer	114	12923.9	2	UniProt (P12643) Pfam (PF00019) In PDB	HOMO SAPIENS (HUMAN)	BMP-2, BONE MORPHOGENETIC PROTEIN 2A, BMP-2A, BONE MORPHOGENETIC PROTEIN 2, BMP2
2	C	REPULSIVE GUIDANCE MOLECULE A	polymer	106	11628.8	1	UniProt (Q96B86) Pfam (PF06535) In PDB	HOMO SAPIENS (HUMAN)	RGM DOMAIN FAMILY MEMBER A, RGMA

Sequence modifications

C: 45 - 140 (UniProt: Q96B86)

PDB	External Database	Details
Glu 43	-	expression tag
Thr 44	-	expression tag
Thr 141	-	expression tag
Lys 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	37476.5
All*	Total formula weight	37476.5

*Water molecules are not included.