PDB: 41454 件ウェブページステータス検索Chemie searchBIRD

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6A4J	Crystal structure of Thioredoxin reductase 2 from Staphylococcus aureus 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase 著者 Bose, M, Bhattacharyya, S, Ghosh, A.K, Das, A.K. 登録日 2018-06-20 公開日 2018-07-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Elucidation of the mechanism of disulfide exchange between staphylococcal thioredoxin2 and thioredoxin reductase2: A structural insight. Biochimie, 160, 2019
8E1E	Scaffolding protein functional sites using deep learning 分子名称: SG122_C3 著者 Bera, A.K, Gerben, S, Baker, D. 登録日 2022-08-10 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (4.27 Å) 主引用文献 Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins. Biochemistry, 62, 2023
6Y3W	Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 1 分子名称: 14-3-3 protein sigma, 3-fluoranyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2020-02-19 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
6Y1D	Binary complex of 14-3-3 sigma (C38N) with the Estrogen Related Receptor gamma (DBD) phosphopeptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Estrogen related receptor gamma phosphopeptide, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2020-02-12 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
7ELG	LC3B modificated with a covalent probe 分子名称: 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION 著者 Fan, S, Wan, W. 登録日 2021-04-10 公開日 2021-10-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
6Y58	Binary complex of 14-3-3 sigma (C38N) with the Estrogen Related Receptor gamma (LBD) phosphopeptide 分子名称: 14-3-3 protein sigma, Estrogen Related Receptor gamma phosphopeptide, MAGNESIUM ION 著者 Somsen, B.A, Sijbesma, E, Leijten-van de Gevel, I.A, Ottmann, C. 登録日 2020-02-25 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.904 Å) 主引用文献 Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
6Y18	Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 3 分子名称: 14-3-3 protein sigma, 4-fluoranyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2020-02-11 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
6XY5	Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 5 分子名称: 14-3-3 protein sigma, 3-bromanyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2020-01-29 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
6XXC	Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 4 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Estrogen Related Receptor gamma phosphopeptide, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2020-01-27 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
7UN8	SfSTING with c-di-GMP single fiber 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12 著者 Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. 登録日 2022-04-09 公開日 2022-07-27 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
7UN9	SfSTING with c-di-GMP double fiber 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12 著者 Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. 登録日 2022-04-09 公開日 2022-07-27 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
7UNA	SfSTING with cGAMP (masked) 分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CD-NTase-associated protein 12 著者 Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. 登録日 2022-04-09 公開日 2022-07-27 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
8JPX	Cryo-EM structure of PfAgo-guide DNA-target DNA complex 分子名称: Excess DNA, Guide DNA, MAGNESIUM ION, ... 著者 Zhuang, L. 登録日 2023-06-13 公開日 2024-01-31 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular mechanism for target recognition, dimerization, and activation of Pyrococcus furiosus Argonaute. Mol.Cell, 84, 2024
4EE2	Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution 分子名称: CALCIUM ION, Protective antigen 著者 Kintzer, A.F, Krantz, B.A. 登録日 2012-03-28 公開日 2012-10-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Anthrax toxin protective antigen integrates poly-gamma-D-glutamate and pH signals to sense the optimal environment for channel formation. Proc.Natl.Acad.Sci.USA, 109, 2012
7QZ7	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5,6,7-trifluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
4U0P	The Crystal Structure of Lipoyl Synthase in Complex with S-Adenosyl Homocysteine 分子名称: IRON/SULFUR CLUSTER, Lipoyl synthase 2, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Harmer, J.E, Hiscox, M.J, Sandy, J, Dinis, P.C, Roach, P.L. 登録日 2014-07-13 公開日 2014-08-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.623 Å) 主引用文献 Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions. Biochem.J., 464, 2014
7QZ9	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
4V0C	Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin 分子名称: CALCIUM ION, CALMODULIN, POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1, ... 著者 Sachyani, D, Hirsch, J.A. 登録日 2014-09-14 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin. Structure, 22, 2014
1MJN	Crystal Structure of the intermediate affinity aL I domain mutant 分子名称: Integrin alpha-L, MAGNESIUM ION 著者 Shimaoka, M, Xiao, T, Liu, J.H, Yang, Y.T, Dong, Y.C, Jun, C.D, McCormack, A, Zhang, R.G, Wang, J.H, Springer, T.A. 登録日 2002-08-28 公開日 2003-01-28 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structures of the alphaL I Domain and its Complex with ICAM-1 reveal a Shape-shifting Pathway for Integrin Regulation Cell(Cambridge,Mass.), 112, 2003
7QZ5	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5-fluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
6L0C	Crystal structure of HIV-1 Integrase catalytic core domain (A128T/K173Q/F185K) 分子名称: ARSENIC, Integrase, SULFATE ION 著者 Nakamura, T, Nakamura, T. 登録日 2019-09-26 公開日 2020-07-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 A Conformational Escape Reaction of HIV-1 against an Allosteric Integrase Inhibitor. J.Virol., 94, 2020
4F3L	Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex 分子名称: BMAL1b, Circadian locomoter output cycles protein kaput 著者 Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J. 登録日 2012-05-09 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.268 Å) 主引用文献 Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex. Science, 337, 2012
4W2O	Anti-Marburgvirus Nucleoprotein Single Domain Antibody B Complexed with Nucleoprotein C-terminal domain 分子名称: Anti-Marburgvirus Nucleoprotein Single Domain Antibody B, Nucleoprotein, SULFATE ION 著者 Taylor, A.B, Garza, J.A. 登録日 2017-08-17 公開日 2017-10-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies. Front Immunol, 8, 2017
4W2P	Anti-Marburgvirus Nucleoprotein Single Domain Antibody C 分子名称: ACETATE ION, Anti-Marburgvirus Nucleoprotein Single Domain Antibody C, SODIUM ION 著者 Taylor, A.B, Garza, J.A. 登録日 2017-08-17 公開日 2017-10-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies. Front Immunol, 8, 2017
4W2Q	Anti-Marburgvirus Nucleoprotein Single Domain Antibody C Complexed with Nucleoprotein C-terminal domain 分子名称: Anti-Marburgvirus Nucleoprotein Single Domain Antibody C, Nucleoprotein 著者 Taylor, A.B, Garza, J.A. 登録日 2017-08-17 公開日 2017-10-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies. Front Immunol, 8, 2017

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