8E1E

Scaffolding protein functional sites using deep learning

Summary for 8E1E

Entry DOI	10.2210/pdb8e1e/pdb
Descriptor	SG122_C3 (1 entity in total)
Functional Keywords	de novo design, scaffolding protein, ligand binding, pocket, de novo protein
Biological source	synthetic construct
Total number of polymer chains	3
Total formula weight	83476.01
Authors	Bera, A.K.,Gerben, S.,Baker, D. (deposition date: 2022-08-10, release date: 2023-08-16)
Primary citation	Gerben, S.R.,Borst, A.J.,Hicks, D.R.,Moczygemba, I.,Feldman, D.,Coventry, B.,Yang, W.,Bera, A.K.,Miranda, M.,Kang, A.,Nguyen, H.,Baker, D. Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins. Biochemistry, 62:358-368, 2023 Cited by PubMed: 36627259 DOI: 10.1021/acs.biochem.2c00497 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.27 Å)

Structure validation