6Y58

Binary complex of 14-3-3 sigma (C38N) with the Estrogen Related Receptor gamma (LBD) phosphopeptide

Summary for 6Y58

Entry DOI	10.2210/pdb6y58/pdb
Descriptor	14-3-3 protein sigma, Estrogen Related Receptor gamma phosphopeptide, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	14-3-3, erry phosphopeptide, peptide binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	27696.92
Authors	Somsen, B.A.,Sijbesma, E.,Leijten-van de Gevel, I.A.,Ottmann, C. (deposition date: 2020-02-25, release date: 2020-11-18, Last modification date: 2024-01-24)
Primary citation	Sijbesma, E.,Somsen, B.A.,Miley, G.P.,Leijten-van de Gevel, I.A.,Brunsveld, L.,Arkin, M.R.,Ottmann, C. Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15:3143-3148, 2020 Cited by PubMed: 33196173 DOI: 10.1021/acschembio.0c00646 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.904 Å)

Structure validation