6XY5

Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 5

Summary for 6XY5

• Entry DOI: 10.2210/pdb6xy5/pdb
• Related: 6XXC
• Descriptor: 14-3-3 protein sigma, Estrogen Related Receptor gamma phosphopeptide, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: 14-3-3, erry phosphopeptide, disulfide, stabilization, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 28129.48

Authors

Somsen, B.A.,Ottmann, C. (deposition date: 2020-01-29, release date: 2020-11-18, Last modification date: 2024-01-24)

• Primary citation: Sijbesma, E.,Somsen, B.A.,Miley, G.P.,Leijten-van de Gevel, I.A.,Brunsveld, L.,Arkin, M.R.,Ottmann, C.; Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers.; Acs Chem.Biol., 15:3143-3148, 2020; PubMed: 33196173; DOI: 10.1021/acschembio.0c00646

Experimental method

X-RAY DIFFRACTION (1.3 Å)