7ELG
LC3B modificated with a covalent probe
Summary for 7ELG
Entry DOI | 10.2210/pdb7elg/pdb |
Descriptor | Microtubule-associated proteins 1A/1B light chain 3B, 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, SULFATE ION, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 14781.89 |
Authors | |
Primary citation | Fan, S.,Yue, L.,Wan, W.,Zhang, Y.,Zhang, B.,Otomo, C.,Li, Q.,Lin, T.,Hu, J.,Xu, P.,Zhu, M.,Tao, H.,Chen, Z.,Li, L.,Ding, H.,Yao, Z.,Lu, J.,Wen, Y.,Zhang, N.,Tan, M.,Chen, K.,Xie, Y.,Otomo, T.,Zhou, B.,Jiang, H.,Dang, Y.,Luo, C. Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60:26105-26114, 2021 Cited by PubMed: 34590387DOI: 10.1002/anie.202109464 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.599 Å) |
Structure validation
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