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4EE2

Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution

Summary for 4EE2
Entry DOI10.2210/pdb4ee2/pdb
Related1ACC 1TZO 3HVD 3TEW 3TEX
DescriptorProtective antigen, CALCIUM ION (3 entities in total)
Functional Keywordsanthrax toxin, cell-binding, assembly, channel formation, protein translocation, toxin, transport protein
Biological sourceBacillus anthracis (anthrax,anthrax bacterium)
Cellular locationSecreted, extracellular space: P13423
Total number of polymer chains1
Total formula weight82982.19
Authors
Kintzer, A.F.,Krantz, B.A. (deposition date: 2012-03-28, release date: 2012-10-24, Last modification date: 2023-09-13)
Primary citationKintzer, A.F.,Tang, I.I.,Schawel, A.K.,Brown, M.J.,Krantz, B.A.
Anthrax toxin protective antigen integrates poly-gamma-D-glutamate and pH signals to sense the optimal environment for channel formation.
Proc.Natl.Acad.Sci.USA, 109:18378-18383, 2012
Cited by
PubMed: 23100533
DOI: 10.1073/pnas.1208280109
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.91 Å)
Structure validation

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