PDB: 1415 件ウェブページステータス検索Chemie searchBIRD

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4NUG	Crystal structure of HIV-1 broadly neutralizing antibody PGT151 分子名称: HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain 著者 Blattner, C, Wilson, I.A. 登録日 2013-12-03 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8617 Å) 主引用文献 Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity, 40, 2014
4NUJ	Crystal structure of HIV-1 broadly neutralizing antibody PGT152 分子名称: PGT152 heavy chain, PGT152 light chain 著者 Blattner, C, Wilson, I.A. 登録日 2013-12-03 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.827 Å) 主引用文献 Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity, 40, 2014
4NWU	Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1 分子名称: APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain 著者 Verdino, P, Stanfield, R.L, Wilson, I.A. 登録日 2013-12-06 公開日 2014-10-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
4NWT	Crystal structure of the anti-human NGF Fab APE1531 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ... 著者 Verdino, P, Stanfield, R.L, Wilson, I.A. 登録日 2013-12-06 公開日 2014-10-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
4O58	Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... 著者 Lee, P.S, Wilson, I.A. 登録日 2013-12-19 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7501 Å) 主引用文献 Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
4O5I	Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ... 著者 Lee, P.S, Wilson, I.A. 登録日 2013-12-19 公開日 2014-04-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (6.501 Å) 主引用文献 Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
4O5L	Crystal structure of broadly neutralizing antibody F045-092 分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION 著者 Lee, P.S, Wilson, I.A. 登録日 2013-12-19 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5045 Å) 主引用文献 Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014
4CKD	Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4. 分子名称: BETA-GALACTOSIDASE, SCFV13R4 ANTIBODY FV HEAVY CHAIN, SCFV13R4 ANTIBODY FV LIGHT CHAIN 著者 Vinothkumar, K.R, McMullan, G, Henderson, R. 登録日 2014-01-03 公開日 2014-01-15 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (13 Å) 主引用文献 Molecular Mechanism of Antibody-Mediated Activation of Beta-Galactosidase. Structure, 22, 2014
4OB5	Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10 分子名称: 4E10 antibody germline precursor 7 heavy chain Fv, 4E10 antibody germline precursor 7 light chain Fv, GLYCEROL, ... 著者 Jaffe, J.B, Rupert, P.B. 登録日 2014-01-06 公開日 2014-10-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10. Plos Pathog., 10, 2014
4OCY	Fab for methotrexate (unbound apo) 分子名称: Fab ADD058 Heavy Chain, Fab ADD058 Light Chain 著者 Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. 登録日 2014-01-09 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
4OCX	Fab complex with methotrexate 分子名称: Fab ADD056 Heavy Chain, Fab ADD056 Light Chain, N-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACID 著者 Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. 登録日 2014-01-09 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
4ODB	Crystal structure of the T1L reovirus attachment protein sigma1 in complex with Junctional Adhesion Molecule-A 分子名称: Junctional adhesion molecule A, Outer capsid protein sigma-1 著者 Stettner, E, Stehle, T. 登録日 2014-01-10 公開日 2015-04-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The JAM-A binding site is conserved in reovirus sigma1: Structure of the T1L sigma1-JAM-A complex To be Published
4ODX	4E10 germline encoded precursor no.7 in complex with epitope scaffold T117 分子名称: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain 著者 Finton, K.A.K. 登録日 2014-01-10 公開日 2014-10-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10. Plos Pathog., 10, 2014
4OFI	Crystal Structure of Duf (Kirre) D1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kin of irre, isoform A, ... 著者 Ozkan, E, Garcia, K.C. 登録日 2014-01-14 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
4OFY	Crystal Structure of the Complex of SYG-1 D1-D2 and SYG-2 D1-D4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL MERCURY ION, ... 著者 Ozkan, E, Garcia, K.C. 登録日 2014-01-15 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
4OGY	Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.1 Angstrom resolution 分子名称: 1,2-ETHANEDIOL, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ... 著者 Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. 登録日 2014-01-16 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
4OGX	Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.4 Angstrom resolution 分子名称: DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, Plasma kallikrein, ... 著者 Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. 登録日 2014-01-16 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
4CMM	Structure of human CD47 in complex with human Signal Regulatory Protein (SIRP) alpha v1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 著者 Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. 登録日 2014-01-16 公開日 2014-02-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Polymorphisms in the Human Inhibitory Signal-Regulatory Protein Alpha Do not Affect Binding to its Ligand Cd47. J.Biol.Chem., 289, 2014
4OQT	LINGO-1/Li81 Fab complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Li81 Fab, ... 著者 Pepinsky, R.B, Arndt, J.W, Quan, C, Gao, Y, Quintero-Monzon, O, Lee, X, Mi, S. 登録日 2014-02-10 公開日 2014-05-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy. J.Pharmacol.Exp.Ther., 350, 2014
2MKW	Solution Structure of 6aJl2 and 6aJL2-R24G Amyloidogenics Light Chain Proteins 分子名称: V1-22 protein 著者 Amero, C, Maya-Martinez, R.C, Gil-Rodriguez, P.C. 登録日 2014-02-13 公開日 2014-06-18 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of 6aJL2 and 6aJL2-R24G amyloidogenics light chain proteins. Biochem.Biophys.Res.Commun., 456, 2015
4OZF	JR5.1 protein complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ... 著者 Petersen, J, Reid, H.H, Rossjohn, J. 登録日 2014-02-15 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4OZI	S2 protein complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HLA class II histocompatibility antigen, ... 著者 Petersen, J, Reid, H.H, Rossjohn, J. 登録日 2014-02-16 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4OZG	D2 protein complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Petersen, J, Reid, H.H, Rossjohn, J. 登録日 2014-02-16 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4OZH	S16 protein complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Gliadin-alpha2 peptide, ... 著者 Petersen, J, Reid, H.H, Rossjohn, J. 登録日 2014-02-16 公開日 2014-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease. Nat.Struct.Mol.Biol., 21, 2014
4P2C	Complex of Shiga toxin 2e with a neutralizing single-domain antibody 分子名称: Nanobody 1, Anti-F4+ETEC bacteria VHH variable region, Shiga toxin 2e, ... 著者 Lo, A.W.H, Moonens, K, De Kerpel, M, Brys, L, Pardon, E, Remaut, H, De Greve, H. 登録日 2014-03-03 公開日 2014-07-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.818 Å) 主引用文献 The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain. J.Biol.Chem., 289, 2014

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