4ODX
4E10 germline encoded precursor no.7 in complex with epitope scaffold T117
Summary for 4ODX
Entry DOI | 10.2210/pdb4odx/pdb |
Descriptor | 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain (3 entities in total) |
Functional Keywords | hiv, 4e10, gep, germline, antibody, fv, immunoglobulin, 4e10 epitope, immune system |
Biological source | artificial gene More |
Total number of polymer chains | 6 |
Total formula weight | 88693.53 |
Authors | |
Primary citation | Finton, K.A.,Friend, D.,Jaffe, J.,Gewe, M.,Holmes, M.A.,Larman, H.B.,Stuart, A.,Larimore, K.,Greenberg, P.D.,Elledge, S.J.,Stamatatos, L.,Strong, R.K. Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10. Plos Pathog., 10:e1004403-e1004403, 2014 Cited by PubMed: 25254371DOI: 10.1371/journal.ppat.1004403 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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