Crystal structure of HIV-1 broadly neutralizing antibody PGT151

Summary for 4NUG

DescriptorPGT151 light chain, PGT151 heavy chain, HEXAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywordsimmunoglobulin, fab fragment, immune system, hiv envelope
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight50709.91
Blattner, C.,Wilson, I.A. (deposition date: 2013-12-03, release date: 2014-05-14, Last modification date: 2017-08-02)
Primary citation
Blattner, C.,Lee, J.H.,Sliepen, K.,Derking, R.,Falkowska, E.,de la Pena, A.T.,Cupo, A.,Julien, J.P.,van Gils, M.,Lee, P.S.,Peng, W.,Paulson, J.C.,Poignard, P.,Burton, D.R.,Moore, J.P.,Sanders, R.W.,Wilson, I.A.,Ward, A.B.
Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40:669-680, 2014
PubMed: 24768348 (PDB entries with the same primary citation)
DOI: 10.1016/j.immuni.2014.04.008
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20620 0.8% 2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21