4CMM
Structure of human CD47 in complex with human Signal Regulatory Protein (SIRP) alpha v1
Summary for 4CMM
Entry DOI | 10.2210/pdb4cmm/pdb |
Descriptor | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, LEUKOCYTE SURFACE ANTIGEN CD47, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | signaling protein, paired receptor, immunological, inhibitory |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 29477.97 |
Authors | Hatherley, D.,Lea, S.M.,Johnson, S.,Barclay, A.N. (deposition date: 2014-01-16, release date: 2014-02-26, Last modification date: 2023-12-20) |
Primary citation | Hatherley, D.,Lea, S.M.,Johnson, S.,Barclay, A.N. Polymorphisms in the Human Inhibitory Signal-Regulatory Protein Alpha Do not Affect Binding to its Ligand Cd47. J.Biol.Chem., 289:10024-, 2014 Cited by PubMed: 24550402DOI: 10.1074/JBC.M114.550558 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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