4OB5

Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10

Summary for 4OB5

• Entry DOI: 10.2210/pdb4ob5/pdb
• Descriptor: 4E10 antibody germline precursor 7 heavy chain Fv, 4E10 antibody germline precursor 7 light chain Fv, GLYCEROL, ... (5 entities in total)
• Functional Keywords: immunoglobulin fold, anti-hiv antibody germline precursor, hiv gp41, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 26238.38

Authors

Jaffe, J.B.,Rupert, P.B. (deposition date: 2014-01-06, release date: 2014-10-08)

• Primary citation: Finton, K.A.,Friend, D.,Jaffe, J.,Gewe, M.,Holmes, M.A.,Larman, H.B.,Stuart, A.,Larimore, K.,Greenberg, P.D.,Elledge, S.J.,Stamatatos, L.,Strong, R.K.; Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.; Plos Pathog., 10:e1004403-e1004403, 2014; PubMed: 25254371; DOI: 10.1371/journal.ppat.1004403

Experimental method

X-RAY DIFFRACTION (1.7 Å)