PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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5NPW	Structure of human ATG5-ATG16L1(ATG5BD) complex (C2) 分子名称: Autophagy protein 5, Autophagy-related protein 16-1 著者 Archna, A, Scrima, A. 登録日 2017-04-19 公開日 2017-10-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Identification, biochemical characterization and crystallization of the central region of human ATG16L1. Acta Crystallogr F Struct Biol Commun, 73, 2017
4IMV	Ricin A-chain variant 1-33/44-198 with engineered disulfide bond, R48C/T77C/D75N 分子名称: Ricin, SULFATE ION 著者 Legler, P.M, Compton, J.R, Millard, C.B. 登録日 2013-01-03 公開日 2013-02-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Disruption of the Putative Vascular Leak Peptide Sequence in the Stabilized Ricin Vaccine Candidate RTA1-33/44-198. Toxins (Basel), 5, 2013
4OLV	Crystal structure of antibody VRC07-G54F in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4ONG	Fab fragment of 3D6 in complex with amyloid beta 1-40 分子名称: 3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ... 著者 Feinberg, H, Saldanha, J.W, Diep, L, Goel, A, Widom, A, Veldman, G.M, Weis, W.I, Schenk, D, Basi, G.S. 登録日 2014-01-28 公開日 2014-06-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab. Alzheimers Res Ther, 6, 2014
4JXW	X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a non-covalent inhibitor 3-{[3-(4-CARBOXYPHENYL)PROPYL]SULFAMOYL}THIOPHENE-2-CARBOXYLIC ACID (compound 6) 分子名称: 3-{[3-(4-carboxyphenyl)propyl]sulfamoyl}thiophene-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Powers, R.A, Hendershot, J.M. 登録日 2013-03-28 公開日 2014-05-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based efforts to optimize a non-beta-lactam inhibitor of AmpC beta-lactamase. Bioorg.Med.Chem., 22, 2014
3BPT	Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin 分子名称: (2R)-3-HYDROXY-2-METHYLPROPANOIC ACID, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, 3-hydroxyisobutyryl-CoA hydrolase 著者 Pilka, E.S, Phillips, C, King, O.N.F, Guo, K, von Delft, F, Pike, A.C.W, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2007-12-19 公開日 2008-01-08 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin. To be Published
4JN1	An Antidote for Dabigatran 分子名称: GLYCEROL, anti-dabigatran Fab1, heavy chain, ... 著者 Schiele, F, Nar, H. 登録日 2013-03-14 公開日 2013-03-27 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 A specific antidote for dabigatran: functional and structural characterization. Blood, 121, 2013
4JQH	Crystal structure of a new sGC activator (analogue of BAY 58-2667) bound to nostoc H-NOX domain 分子名称: 4-{[(4-carboxybutyl)(2-{2-[(4'-phenoxybiphenyl-4-yl)methoxy]phenyl}ethyl)amino]methyl}benzoic acid, Alr2278 protein, MALONIC ACID 著者 Kumar, V, van den Akker, F. 登録日 2013-03-20 公開日 2013-11-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insights into soluble guanylyl cyclase activation derived from improved heme-mimetics. J.Med.Chem., 56, 2013
4KIS	Crystal Structure of a LSR-DNA Complex 分子名称: CALCIUM ION, DNA (26-MER), Putative integrase [Bacteriophage A118], ... 著者 Rutherford, K, Yuan, P, Perry, K, Van Duyne, G.D. 登録日 2013-05-02 公開日 2013-07-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res., 41, 2013
4OX6	Structure of Synechococcus elongatus PCC 7942 CcmK4 分子名称: Carbon dioxide concentrating mechanism protein CcmK 著者 Sutter, M, Kinney, J.N, Cai, F, Kerfeld, C.A. 登録日 2014-02-04 公開日 2014-08-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.3367 Å) 主引用文献 Engineering bacterial microcompartment shells: chimeric shell proteins and chimeric carboxysome shells. Acs Synth Biol, 4, 2015
4OLY	Crystal structure of antibody VRC07-G54R in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4MW2	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1472) 分子名称: 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
4MNN	The crystal structure of Sso1120 from Sulfolobus solfataricus 分子名称: GLYCEROL, Glutaredoxin related protein 著者 D'Ambrosio, K, De Simone, G. 登録日 2013-09-11 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Sulfolobus solfataricus thiol redox puzzle: characterization of an atypical protein disulfide oxidoreductase. Extremophiles, 18, 2014
4BEA	Crystal Structure of eIF4E in Complex with a Stapled Peptide Derivative 分子名称: Eukaryotic translation initiation factor 4E, STAPLED EIF4E INTERACTING PEPTIDE 著者 Quah, S.T, Lama, D, Verma, C.S, Lane, D.P, Brown, C.J. 登録日 2013-03-07 公開日 2013-12-11 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Rational Optimization of Conformational Effects Induced by Hydrocarbon Staples in Peptides and Their Binding Interfaces. Sci.Rep., 3, 2013
4MW7	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1469) 分子名称: 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
4MN4	Structural Basis for the MukB-topoisomerase IV Interaction 分子名称: Chromosome partition protein MukB, DNA topoisomerase 4 subunit A 著者 Vos, S.M, Stewart, N.K, Oakley, M.G, Berger, J.M. 登録日 2013-09-09 公開日 2013-10-23 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo. Embo J., 32, 2013
4K0A	Crystal structure of CD4-mimetic miniprotein M48U7 in complex with HIV-1 YU2 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U7, CITRATE ANION, ... 著者 Acharya, P, Kwong, P.D. 登録日 2013-04-03 公開日 2013-06-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1. Structure, 21, 2013
4MW0	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea (Chem 1392) 分子名称: 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-(2-hydroxyphenyl)urea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
5XFQ	Ternary complex of PHF1, a DNA duplex and a histone peptide 分子名称: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, Peptide from Histone H3, ... 著者 Wang, Z, Li, H. 登録日 2017-04-11 公開日 2017-09-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
4AZA	Improved eIF4E binding peptides by phage display guided design. 分子名称: EIF4G1_D5S PEPTIDE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE 著者 Chew, W.Z, Quah, S.T, Verma, C.S, Liu, Y, Lane, D.P, Brown, C.J. 登録日 2012-06-25 公開日 2012-08-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Improved Eif4E Binding Peptides by Phage Display Guided Design: Plasticity of Interacting Surfaces Yield Collective Effects. Plos One, 7, 2012
4MW6	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[2-(benzyloxy)-5-chloro-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1476) 分子名称: 1-(3-{[2-(benzyloxy)-5-chloro-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.558 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
4H20	Crystal Structure and Computational Modeling of the Fab Fragment from the Protective anti-Ricin Monoclonal Antibody RAC18 分子名称: Heavy chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18, Light chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18 著者 Zhao, Z, Worthylake, D.K, LeCour Jr, L.F, Maresh, G, Pincus, S.H. 登録日 2012-09-11 公開日 2012-10-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody. Plos One, 7, 2012
4MYW	Structure of HSV-2 gD bound to nectin-1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... 著者 Lu, G, Zhang, N, Qi, J, Li, Y, Chen, Z, Zheng, C, Yan, J, Gao, G.F. 登録日 2013-09-28 公開日 2014-10-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.189 Å) 主引用文献 Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition. J.Virol., 88, 2014
4HD5	Crystal Structure of BC0361, a polysaccharide deacetylase from Bacillus cereus 分子名称: ACETATE ION, Polysaccharide deacetylase, ZINC ION 著者 Fadouloglou, V.E, Kokkinidis, M, Glykos, N.M. 登録日 2012-10-02 公開日 2012-10-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure determination through homology modelling and torsion-angle simulated annealing: application to a polysaccharide deacetylase from Bacillus cereus. Acta Crystallogr.,Sect.D, 69, 2013
4MW5	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea (Chem 1415) 分子名称: 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.347 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014

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