4BEA

Crystal Structure of eIF4E in Complex with a Stapled Peptide Derivative

Summary for 4BEA

Entry DOI	10.2210/pdb4bea/pdb
Descriptor	Eukaryotic translation initiation factor 4E, STAPLED EIF4E INTERACTING PEPTIDE (3 entities in total)
Functional Keywords	translation
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, P-body : P06730
Total number of polymer chains	2
Total formula weight	26691.23
Authors	Quah, S.T.,Lama, D.,Verma, C.S.,Lane, D.P.,Brown, C.J. (deposition date: 2013-03-07, release date: 2013-12-11, Last modification date: 2024-02-07)
Primary citation	Lama, D.,Quah, S.T.,Verma, C.S.,Lakshminarayanan, R.,Beuerman, R.W.,Lane, D.P.,Brown, C.J. Rational Optimization of Conformational Effects Induced by Hydrocarbon Staples in Peptides and Their Binding Interfaces. Sci.Rep., 3:3451-, 2013 Cited by PubMed: 24336354 DOI: 10.1038/SREP03451 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.57 Å)

Structure validation