4AZA

Improved eIF4E binding peptides by phage display guided design.

Summary for 4AZA

Entry DOI	10.2210/pdb4aza/pdb
Related	1IPB 1IPC 2V8W 2V8X 2V8Y 2W97
Descriptor	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EIF4G1_D5S PEPTIDE, [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE, ... (4 entities in total)
Functional Keywords	translation
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm, P-body: P06730
Total number of polymer chains	4
Total formula weight	54478.71
Authors	Chew, W.Z.,Quah, S.T.,Verma, C.S.,Liu, Y.,Lane, D.P.,Brown, C.J. (deposition date: 2012-06-25, release date: 2012-08-08, Last modification date: 2023-12-20)
Primary citation	Zhou, W.,Quah, S.T.,Verma, C.S.,Liu, Y.,Lane, D.P.,Brown, C.J. Improved Eif4E Binding Peptides by Phage Display Guided Design: Plasticity of Interacting Surfaces Yield Collective Effects. Plos One, 7:47235-, 2012 Cited by PubMed: 23094039 DOI: 10.1371/JOURNAL.PONE.0047235 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation