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4AZA

Improved eIF4E binding peptides by phage display guided design.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CEUKARYOTIC TRANSLATION INITIATION FACTOR 4Epolymer21725130.22UniProt (P06730)
Pfam (PF01652)
In PDB
HOMO SAPIENS (HUMAN)EIF-4E, EIF4E, EIF-4F 25 KDA SUBUNIT, MRNA CAP-BINDING PROTEIN
2B, DEIF4G1_D5S PEPTIDEpolymer141571.92UniProt (by SIFTS) (Q04637)
In PDB
HOMO SAPIENS
3A, C[[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATEnon-polymer537.22Chemie (MGO)
4waterwater18.0218Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight53404.3
Non-Polymers*Number of molecules2
Total formula weight1074.5
All*Total formula weight54478.7
*Water molecules are not included.

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PDB entries from 2024-07-24

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