4AZA
Improved eIF4E binding peptides by phage display guided design.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | polymer | 217 | 25130.2 | 2 | UniProt (P06730) Pfam (PF01652) | HOMO SAPIENS (HUMAN) | EIF-4E, EIF4E, EIF-4F 25 KDA SUBUNIT, MRNA CAP-BINDING PROTEIN |
| 2 | B, D (B, D) | EIF4G1_D5S PEPTIDE | polymer | 14 | 1571.9 | 2 | UniProt (by SIFTS) (Q04637) | HOMO SAPIENS | |
| 3 | E, F (A, C) | [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE | non-polymer | 537.2 | 2 | Chemie (MGO) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53404.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1074.5 | |
| All* | Total formula weight | 54478.7 |
