PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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6TKZ	Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42 分子名称: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL, ... 著者 Barford, D. 登録日 2019-11-29 公開日 2020-01-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022
7L9P	Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pachytene checkpoint protein 2 homolog, ... 著者 Xie, W, Patel, D.J. 登録日 2021-01-04 公開日 2021-03-03 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
7Z20	70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia and a stalled filamin domain 5 nascent chain 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. 登録日 2022-02-25 公開日 2022-08-10 実験手法 ELECTRON MICROSCOPY (2.29 Å) 主引用文献 Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
7ZP8	70S E. coli ribosome with a stalled filamin domain 5 nascent chain 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Chan, S.H.S, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. 登録日 2022-04-26 公開日 2022-08-10 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
8C4A	Structural and interactional insights into the glideosome-associated connector from Toxoplasma gondii 分子名称: Putative anonymous antigen-1 著者 Kumar, A, Morgan, R.M.L, Matthews, S.J. 登録日 2023-01-03 公開日 2023-07-19 実験手法 X-RAY DIFFRACTION (2.675 Å) 主引用文献 Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii. Elife, 12, 2023
5N6O	Wild type human Rac1-GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 著者 Cherfils, J, Ferrandez, Y. 登録日 2017-02-15 公開日 2017-12-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule. Sci Rep, 7, 2017
3TBJ	The 1.7A crystal structure of Actibind a T2 ribonucleases as antitumorigenic agents 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Almog, O, Gonzalez, A. 登録日 2011-08-07 公開日 2012-08-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The 1.8 A crystal structure of ACTIBIND suggests a mode of action for T2 ribonucleases as antitumorigenic agents. J.Med.Chem., 55, 2012
3REP	Crystal structure of the ILK/alpha-parvin core complex (MnATP) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Alpha-parvin, Integrin-linked kinase, ... 著者 Fukuda, K, Qin, J. 登録日 2011-04-04 公開日 2011-04-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the ILK/alpha-parvin core complex (MnATP) To be Published
3CNK	Crystal Structure of the dimerization domain of human filamin A 分子名称: Filamin-A, SULFATE ION 著者 Lee, B.J, Seo, M.D, Seok, S.H, Lee, S.J, Kwon, A.R, Im, H. 登録日 2008-03-26 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the dimerization domain of human filamin A Proteins, 75, 2008
6WWA	Crystal structure of human SHLD2-SHLD3-REV7 complex 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera 著者 Xie, W, Patel, D.J. 登録日 2020-05-08 公開日 2021-03-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
6UI4	Crystal structure of phenamacril-bound F. graminearum myosin I 分子名称: Calmodulin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Zhou, Y, Zhou, X.E, Gong, Y, Zhu, Y, Xu, H.E, Zhou, M, Melcher, K, Zhang, F. 登録日 2019-09-30 公開日 2020-03-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis of Fusarium myosin I inhibition by phenamacril. Plos Pathog., 16, 2020
6KEA	crystal structure of MBP-tagged REV7-IpaB complex 分子名称: Maltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3 著者 Wang, X, Pernicone, N, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. 登録日 2019-07-04 公開日 2019-09-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294, 2019
6KFT	MVM NS2 mutant Nm42 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Sun, Q, Li, Y. 登録日 2019-07-08 公開日 2020-07-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6KC4	Crystal structure of human Fer SH2 domain bound to a phosphopeptide (DEpYENVD) 分子名称: Tyrosine-protein kinase Fer, phosphopeptide (EDpYENVD) 著者 Matsuura, Y. 登録日 2019-06-27 公開日 2019-09-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 High-resolution structural analysis shows how different crystallographic environments can induce alternative modes of binding of a phosphotyrosine peptide to the SH2 domain of Fer tyrosine kinase. Protein Sci., 28, 2019
1P2X	CRYSTAL STRUCTURE OF THE CALPONIN-HOMOLOGY DOMAIN OF RNG2 FROM SCHIZOSACCHAROMYCES POMBE 分子名称: BROMIDE ION, Ras GTPase-activating-like protein 著者 Wang, C.-H, Balasubramanian, M.K, Dokland, T. 登録日 2003-04-16 公開日 2004-06-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure, crystal packing and molecular dynamics of the calponin-homology domain of Schizosaccharomyces pombe Rng2. Acta Crystallogr.,Sect.D, 60, 2004
5XR1	Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2 分子名称: C-terminal peptide of Integrin beta-2,Filamin-A IG21 domain 著者 Chatterjee, D, Lu, L.Z, Bhattacharjya, S. 登録日 2017-06-07 公開日 2018-06-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2 To Be Published
6E5N	Solution structure of human Myosin VI isoform 3 (1050-1131) in complex with Clathrin light chain a (46-61) 分子名称: Clathrin light chain A, Unconventional myosin-VI 著者 Buel, G.R, Walters, K.J. 登録日 2018-07-20 公開日 2019-11-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension. Nat Commun, 10, 2019
2YIN	STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1. 分子名称: DEDICATOR OF CYTOKINESIS PROTEIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 著者 Kulkarni, K.A, Yang, J, Zhang, Z, Barford, D. 登録日 2011-05-16 公開日 2011-05-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (Dock) Nucleotide Exchange Factors. J.Biol.Chem., 286, 2011
3BJI	Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 分子名称: Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION 著者 Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) 登録日 2007-12-04 公開日 2008-07-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J.Mol.Biol., 380, 2008
1P5S	STRUCTURE AND FUNCTION OF THE CALPONIN-HOMOLOGY DOMAIN OF AN IQGAP PROTEIN FROM SCHIZOSACCHAROMYCES POMBE 分子名称: MERCURY (II) ION, Ras GTPase-activating-like protein rng2 著者 Wang, C.H, Balasubramanian, M.K, Dokland, T. 登録日 2003-04-28 公開日 2004-05-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structure, crystal packing and molecular dynamics of the calponin-homology domain of Schizosaccharomyces pombe Rng2. Acta Crystallogr.,Sect.D, 60, 2004
7S0Y	Structures of TcdB in complex with Cdc42 分子名称: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Zheng, L, Rongsheng, J, Peng, C. 登録日 2021-08-31 公開日 2021-09-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B. Sci Adv, 7, 2021
8OQI	Cryo-EM structure of the wild-type alpha-synuclein fibril. 分子名称: Alpha-synuclein 著者 Pesch, V, Reithofer, S, Ma, L, Flores-Fernandez, J.M, Oezduezenciler, P, Busch, Y, Lien, Y, Rudtke, O, Frieg, B, Schroeder, G.F, Wille, H, Tamgueney, G. 登録日 2023-04-12 公開日 2024-03-13 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson's disease. Brain, 147, 2024
7STY	Crystal structure of human CORO1C 分子名称: Coronin-1C 著者 Zeng, H, Dong, A, Hutchinson, A, Seitova, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) 登録日 2021-11-15 公開日 2021-12-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of human CORO1C To Be Published
8Q6T	Helical reconstruction of the relaxed thick filament from FIB milled left ventricular mouse myofibrils 分子名称: Myosin binding protein C, cardiac, Myosin light chain 3, ... 著者 Tamborrini, D, Raunser, S. 登録日 2023-08-14 公開日 2023-11-01 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (18 Å) 主引用文献 Structure of the native myosin filament in the relaxed cardiac sarcomere. Nature, 623, 2023
8PJN	Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin 分子名称: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ... 著者 Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A. 登録日 2023-06-23 公開日 2024-01-03 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Mol.Cell, 84, 2024

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