PDB: 17019 件ウェブページステータス検索Chemie searchBIRD

---

7AUG	Crystal structure of rsGCamP1.3 in the ON state 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, FORMIC ACID, ... 著者 Janowski, R, Fuenzalida-Werner, J.P, Mishra, K, Stiel, A.C, Niessing, D. 登録日 2020-11-03 公開日 2021-10-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging. Nat.Biotechnol., 40, 2022
6L7K	solution structure of hIFABP V60C/Y70C variant. 分子名称: Fatty acid-binding protein, intestinal 著者 Fan, J, Yang, D. 登録日 2019-11-01 公開日 2020-11-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Ligand Entry into Fatty Acid Binding Protein via Local Unfolding Instead of Gap Widening. Biophys.J., 118, 2020
6RP9	Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV 分子名称: Beta-2-microglobulin, Cancer/testis antigen 1, HLA class I histocompatibility antigen, ... 著者 Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. 登録日 2019-05-14 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
1IOP	INCORPORATION OF A HEMIN WITH THE SHORTEST ACID SIDE-CHAINS INTO MYOGLOBIN 分子名称: 6,7-DICARBOXYL-1,2,3,4,5,8-HEXAMETHYLHEMIN, CYANIDE ION, MYOGLOBIN, ... 著者 Igarashi, N, Neya, S, Funasaki, N, Tanaka, N. 登録日 1997-12-12 公開日 1998-04-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and function of 6,7-dicarboxyheme-substituted myoglobin Biochemistry, 37, 1998
8E3Y	Cryo-EM structure of the VPAC1R-PACAP27-Gs complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Piper, S.J, Danev, R, Sexton, P, Wootten, D. 登録日 2022-08-17 公開日 2022-11-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Understanding VPAC receptor family peptide binding and selectivity. Nat Commun, 13, 2022
3MSS	Abl kinase in complex with imatinib and fragment (FRAG2) in the myristate site 分子名称: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, O-benzyl-N-methyl-L-tyrosinamide, Tyrosine-protein kinase ABL1 著者 Cowan-Jacob, S.W, Rummel, G, Fendrich, G. 登録日 2010-04-29 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Binding or bending: distinction of allosteric Abl kinase agonists from antagonists by an NMR-based conformational assay. J.Am.Chem.Soc., 132, 2010
6YLZ	X-ray structure of the K72I,Y129F,R133L, H199A quadruple mutant of PNP-oxidase from E. coli 分子名称: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, Pyridoxine/pyridoxamine 5'-phosphate oxidase, ... 著者 Battista, T, Sularea, M, Barile, A, Fiorillo, A, Tramonti, A, Ilari, A. 登録日 2020-04-07 公開日 2021-04-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.558 Å) 主引用文献 Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase. J.Biol.Chem., 296, 2021
6YMH	X-ray structure of the K72I, Y129F, R133L, H199A quadruple mutant of PNP-oxidase from E. coli in complex with PLP 分子名称: FLAVIN MONONUCLEOTIDE, PYRIDOXAL-5'-PHOSPHATE, Pyridoxine/pyridoxamine 5'-phosphate oxidase, ... 著者 Battista, T, Sularea, M, Barile, A, Fiorillo, A, Tramonti, A, Ilari, A. 登録日 2020-04-08 公開日 2021-04-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.417 Å) 主引用文献 Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase. J.Biol.Chem., 296, 2021
7OQD	A single sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium (BT1636-S1_20) 分子名称: 3-O-sulfo-beta-D-galactopyranose, Arylsulfatase, CALCIUM ION 著者 Sofia de Jesus Vaz Luis, A, Basle, A, Martens, E.C, Cartmell, A. 登録日 2021-06-03 公開日 2021-10-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A single sulfatase is required to access colonic mucin by a gut bacterium. Nature, 598, 2021
8UFO	Crystal Structure of Gastrointestinal HAstV VA1 capsid spike domain at 1.46 A resolution 分子名称: Capsid polyprotein VP90 著者 Ghosh, A, DuBois, R.M. 登録日 2023-10-04 公開日 2024-02-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Structure and antigenicity of the divergent human astrovirus VA1 capsid spike. Plos Pathog., 20, 2024
8G4S	40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V2 conformation with mRNA and three tRNAs. 分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... 著者 Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. 登録日 2023-02-10 公開日 2024-01-31 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
8OV6	Ternary structure of intramolecular bivalent glue degrader IBG1 bound to BRD4 and DCAF16:DDB1deltaBPB 分子名称: Bromodomain-containing protein 4, DDB1- and CUL4-associated factor 16, DDB1deltaBPB, ... 著者 Cowan, A.D, Sundaramoorthy, R, Nakasone, M.A, Ciulli, A. 登録日 2023-04-25 公開日 2023-05-17 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.77 Å) 主引用文献 Targeted protein degradation via intramolecular bivalent glues. Nature, 627, 2024
6VN7	Cryo-EM structure of an activated VIP1 receptor-G protein complex 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Duan, J, Shen, D.-D, Zhou, X.E, Liu, Q.-F, Zhuang, Y.-W, Zhang, H.-B, Xu, P.-Y, Ma, S.-S, He, X.-H, Melcher, K, Zhang, Y, Xu, H.E, Yi, J. 登録日 2020-01-29 公開日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy. Nat Commun, 11, 2020
4EN4	Crystal Structure of the Ternary Human PL Kinase-Ginkgotoxin-MgATP Complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Safo, M.K, Musayev, F.N, Gandhi, A.K. 登録日 2012-04-12 公開日 2012-05-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. Plos One, 7, 2012
7L99	Crystal structure of BRDT bromodomain 2 in complex with CDD-1302 分子名称: Bromodomain testis-specific protein, N-[3-(acetylamino)-4-methylphenyl]-3-(4-amino-2-methylphenyl)-1-methyl-1H-indazole-5-carboxamide, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) 著者 Sharma, R, Yu, Z, Ku, A.F, Anglin, J.L, Ucisik, M.N, Faver, J.C, Sankaran, B, Kim, C, Matzuk, M.M. 登録日 2021-01-03 公開日 2021-06-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proc.Natl.Acad.Sci.USA, 118, 2021
7L9A	Crystal structure of BRDT bromodomain 2 in complex with CDD-1102 分子名称: BETA-MERCAPTOETHANOL, Bromodomain testis-specific protein, N~1~-(5-{[3-(4-amino-2-methylphenyl)-1-methyl-1H-indazole-5-carbonyl]amino}-2-methylphenyl)-N~4~-methylbenzene-1,4-dicarboxamide 著者 Sharma, R, Kaur, G, Yu, Z, Ku, A.F, Anglin, J.L, Ucisik, M.N, Faver, J.C, Sankaran, B, Kim, C, Matzuk, M.M. 登録日 2021-01-03 公開日 2021-06-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proc.Natl.Acad.Sci.USA, 118, 2021
1T8V	The NMR structure of d34a i-fabp: implications for the determinants of ligand binding stoichiometry 分子名称: Fatty acid-binding protein, intestinal 著者 Ogbay, B, Cistola, D.P. 登録日 2004-05-13 公開日 2005-10-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 THE NMR STRUCTURE OF D34A I-FABP: IMPLICATIONS FOR THE DETERMINANTS OF LIGAND BINDING STOICHIOMETRY To be published
4EOH	Crystal Structure of Human PL Kinase with bound Theophylline 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Pyridoxal Kinase, SODIUM ION, ... 著者 Safo, M.K, Gandhi, A.K, Musayev, F.N. 登録日 2012-04-14 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. Plos One, 7, 2012
1T76	Crystal structure of the androgen receptor ligand binding domain in complex with a WxxVW motif 分子名称: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ... 著者 Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. 登録日 2004-05-08 公開日 2004-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Recognition and accommodation at the androgen receptor coactivator binding interface. Plos Biol., 2, 2004
5O38	Human Brd2(BD2) mutant in free form 分子名称: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, 3-[(2~{R})-2-oxidanylpropoxy]-2-[[(2~{R})-2-oxidanylpropoxy]methyl]-2-[[(2~{S})-2-oxidanylpropoxy]methyl]propan-1-ol, Bromodomain-containing protein 2, ... 著者 Chan, K.-H, Runcie, A.C, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
5O3C	Human Brd2(BD2) mutant in complex with 9-Me 分子名称: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... 著者 Runcie, A.C, Chan, K.-H, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
6OZH	Crystal structure of Ciona intestinalis (Ci) Endonuclease V in complex with a 24mer DNA containing an inosine followed by a ribo-adenosine 分子名称: CALCIUM ION, DNA/RNA (5'-D(P*CP*GP*GP*TP*AP*AP*CP*CP*GP*I)-R(P*A)-D(P*TP*AP*TP*GP*CP*AP*GP*CP*AP*TP*TP*TP*C)-3'), endonuclease V isoform X2 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.026 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6OZI	Crystal structure of Ciona intestinalis (Ci) Endonuclease V (D234N) in complex with a 23mer DNA containing an inosine followed by a ribo-adenosine 分子名称: DNA/RNA (23-MER), POTASSIUM ION, TRIETHYLENE GLYCOL, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
5O3D	Human Brd2(BD2) mutant in complex with 9-ET 分子名称: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... 著者 Chan, K.-H, Runcie, A.C, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
5O39	Human Brd2(BD2) mutant in complex with ME 分子名称: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... 著者 Runcie, A.C, Chan, K.-H, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018

<19202122232425262728293031323334>