4EN4

Crystal Structure of the Ternary Human PL Kinase-Ginkgotoxin-MgATP Complex

Summary for 4EN4

• Entry DOI: 10.2210/pdb4en4/pdb
• Related: 2YXU 4EOH
• Descriptor: Pyridoxal kinase, MAGNESIUM ION, SODIUM ION, ... (9 entities in total)
• Functional Keywords: transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: O00764
• Total number of polymer chains: 2
• Total formula weight: 73622.29

Authors

Safo, M.K.,Musayev, F.N.,Gandhi, A.K. (deposition date: 2012-04-12, release date: 2012-05-02, Last modification date: 2024-03-13)

• Primary citation: Gandhi, A.K.,Desai, J.V.,Ghatge, M.S.,di Salvo, M.L.,Di Biase, S.,Danso-Danquah, R.,Musayev, F.N.,Contestabile, R.,Schirch, V.,Safo, M.K.; Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition.; Plos One, 7:e40954-e40954, 2012; PubMed: 22879864; DOI: 10.1371/journal.pone.0040954

Experimental method

X-RAY DIFFRACTION (2.15 Å)