6YMH

X-ray structure of the K72I, Y129F, R133L, H199A quadruple mutant of PNP-oxidase from E. coli in complex with PLP

This is a non-PDB format compatible entry.

Summary for 6YMH

• Entry DOI: 10.2210/pdb6ymh/pdb
• Related: 6YLZ
• Descriptor: Pyridoxine/pyridoxamine 5'-phosphate oxidase, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: pyridoxal 5'-phosphate, vitamine b6 metabolism, oxidase, flavoprotein
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 52140.02

Authors

Battista, T.,Sularea, M.,Barile, A.,Fiorillo, A.,Tramonti, A.,Ilari, A. (deposition date: 2020-04-08, release date: 2021-04-28, Last modification date: 2024-01-24)

• Primary citation: Barile, A.,Battista, T.,Fiorillo, A.,di Salvo, M.L.,Malatesta, F.,Tramonti, A.,Ilari, A.,Contestabile, R.; Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase.; J.Biol.Chem., 296:100795-100795, 2021; PubMed: 34019876; DOI: 10.1016/j.jbc.2021.100795

Experimental method

X-RAY DIFFRACTION (2.417 Å)