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4KFZ
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Crystal structure of LMO2 and anti-LMO2 VH complex
分子名称: Anti-LMO2 VH, LMO-2, ZINC ION
著者Sewell, H, Tanaka, T, El Omari, K, Cruz-Migoni, A, Mancini, E.J, Fuentes-Fernandez, N, Chambers, J, Rabbitts, T.H.
登録日2013-04-28
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.
Sci Rep, 4, 2014
4KKB
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BU of 4kkb by Molmil
Structure of the E148A mutant of CLC-ec1 deltaNC construct in 20mM fluoride and 20mM Bromide
分子名称: Fab, heavy chain, light chain, ...
著者Lim, H.-H, Miller, C.
登録日2013-05-05
公開日2013-08-21
最終更新日2013-11-13
実験手法X-RAY DIFFRACTION (3.021 Å)
主引用文献Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KKN
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Crystal structure of bovine CTLA-4, PSI-NYSGRC-012704
分子名称: Cytotoxic T-lymphocyte associated protein 4, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Kumar, P.R, Ahmed, M, Banu, R, Bhosle, R, Bonanno, J, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Scott Glenn, A, Hammonds, J, Hillerich, B, Khafizov, K, Lafleur, J, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Toro, R, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
登録日2013-05-06
公開日2013-06-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.253 Å)
主引用文献Crystal structure of bovine CTLA-4, PSI-NYSGRC-012704
to be published
4KVC
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2H2 Fab fragment of immature Dengue virus
分子名称: Ig heavy chain V region MOPC 21, Igh protein, Ig kappa chain V-V region MOPC 21, ...
著者Wang, Z, Rossmann, M.G.
登録日2013-05-22
公開日2013-07-24
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody.
J.Virol., 87, 2013
4L1H
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BU of 4l1h by Molmil
Bence-Jones immunoglobulin REI variable portion with seven point mutations
分子名称: Ig kappa chain V-I region Rei
著者Uson, I.
登録日2013-06-03
公開日2014-06-04
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Bence-Jones immunoglobulin REI variable portion with seven point mutations
To be Published
4L1D
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Voltage-gated sodium channel beta3 subunit Ig domain
分子名称: Sodium channel subunit beta-3
著者Namadurai, S, Weimhofer, M, Rajappa, R, Stott, K, Klingauf, J, Chirgadze, D.Y, Jackson, A.P.
登録日2013-06-03
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure and Molecular Imaging of the Nav Channel beta 3 Subunit Indicates a Trimeric Assembly.
J.Biol.Chem., 289, 2014
4L4V
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BU of 4l4v by Molmil
Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH
分子名称: 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J.
登録日2013-06-09
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013
3J42
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Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody
分子名称: Envelope protein E, Ig heavy chain V region MOPC 21, Igh protein chimera, ...
著者Wang, Z, Pennington, J.G, Jiang, W, Rossmann, M.G.
登録日2013-06-13
公開日2013-07-17
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (21 Å)
主引用文献Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody.
J.Virol., 87, 2013
4L8S
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Crystal structure of a human Valpha7.2/Vbeta13.3 MAIT TCR in complex with bovine MR1
分子名称: Beta-2-microglobulin, MHC class I-related protein, Muccosal Associated Invariant T Cell Receptor alpha chain, ...
著者Lopez-Sagaseta, J, Adams, E.J.
登録日2013-06-17
公開日2013-10-16
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1.
J.Immunol., 191, 2013
4L9L
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Crystal structure of a human Valpha7.2/Vbeta13.2 MAIT TCR in complex with bovine MR1
分子名称: Beta-2-microglobulin, MHC class I-related protein, Human MAIT TCR alpha chain, ...
著者Lopez-Sagaseta, J, Adams, E.J.
登録日2013-06-18
公開日2013-10-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1.
J.Immunol., 191, 2013
4LAJ
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BU of 4laj by Molmil
Crystal structure of HIV-1 YU2 envelope gp120 glycoprotein in complex with CD4-mimetic miniprotein, M48U1, and llama single-domain, broadly neutralizing, co-receptor binding site antibody, JM4
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINOHEXANOIC ACID, ...
著者Acharya, P, Luongo, T.S, Kwong, P.D.
登録日2013-06-20
公開日2013-08-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites.
J.Virol., 87, 2013
4LCC
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BU of 4lcc by Molmil
Crystal structure of a human MAIT TCR in complex with a bacterial antigen bound to humanized bovine MR1
分子名称: 1-deoxy-1-[6-(hydroxymethyl)-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl]-D-arabinitol, Beta-2-microglobulin, MHC class I-related protein, ...
著者Lopez-Sagaseta, J, Adams, E.J.
登録日2013-06-21
公開日2013-10-16
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.263 Å)
主引用文献MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1.
J.Immunol., 191, 2013
4LCW
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BU of 4lcw by Molmil
The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH
分子名称: 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Patel, O, Rossjohn, J.
登録日2013-06-24
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.
J.Exp.Med., 210, 2013
4LFH
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Crystal Structure of 9C2 TCR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9C2 TCR delta chain, 9C2 TCR gamma chain, ...
著者Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I.
登録日2013-06-26
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献CD1d-lipid antigen recognition by the gamma delta TCR.
Nat.Immunol., 14, 2013
3WE6
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BU of 3we6 by Molmil
Crystal structure of anti-Prostaglandin E2 Fab fragment
分子名称: ISOPROPYL ALCOHOL, mAb Fab H fragment, mAb Fab L fragment
著者Sugahara, M, Ago, H, Saino, H, Miyano, M.
登録日2013-07-01
公開日2014-07-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of anti-Prostaglandin E2 Fab fragment with Prostaglandin E2
To be Published
4LHU
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Crystal Structure of 9C2 TCR bound to CD1d
分子名称: (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I.
登録日2013-07-01
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献CD1d-lipid antigen recognition by the gamma delta TCR.
Nat.Immunol., 14, 2013
4LKX
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Humanized antibody 4B12 Fab complexed with a CemX segment
分子名称: CemX segment, Fab fragment heavy chain, Fab fragment light chain
著者Chu, H.M, Wright, J, Chan, Y.H, Lin, C.J, Chang, T.W, Lim, C.
登録日2013-07-09
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.
Nat Commun, 5, 2014
4LLY
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BU of 4lly by Molmil
Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A
分子名称: GLYCEROL, MAGNESIUM ION, light chain Clambda, ...
著者Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
登録日2013-07-09
公開日2014-01-29
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLU
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BU of 4llu by Molmil
Structure of Pertuzumab Fab with light chain Clambda at 2.16A
分子名称: ACETATE ION, Light chain CLAMBDA, PERTUZUMAB FAB Heavy chain, ...
著者Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
登録日2013-07-09
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LLW
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Crystal structure of Pertuzumab Clambda Fab with variable domain redesign (VRD2) at 1.95A
分子名称: SULFATE ION, light chain Clambda, mutated Pertuzumab Fab heavy chain
著者Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S.
登録日2013-07-09
公開日2014-01-29
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
4LRN
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BU of 4lrn by Molmil
Ontogeny of recognition specificity and functionality for the anti-HIV antibody 4E10
分子名称: GEP 1 heavy chain, GEP 1 light chain
著者Finton, K.A.K.
登録日2013-07-20
公開日2014-10-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
4M1D
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Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 cyclic peptide MN
分子名称: Cyclic V3 Arch Peptide, Fab mAb 447-52D Heavy Chain, Fab mAb 447-52D Light Chain, ...
著者Killikelly, A, Kong, X.P.
登録日2013-08-02
公開日2013-09-04
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Thermodynamic Signatures of the Antigen Binding Site of mAb 447-52D Targeting the Third Variable Region of HIV-1 gp120.
Biochemistry, 52, 2013
4M62
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Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10
分子名称: GEP2 FV heavy chain, GEP2 FV light chain, SULFATE ION, ...
著者Finton, K.A.K.
登録日2013-08-08
公開日2014-10-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
4M8Q
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Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10
分子名称: 4E10 epitope scaffold T117, GEP1 Fv heavy chain, GEP1 Fv light chain
著者Finton, K.A.K.
登録日2013-08-13
公開日2014-10-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
4MJI
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T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01
分子名称: Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Motozono, C, Takiguchi, M.
登録日2013-09-03
公開日2014-05-28
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01
J.Immunol., 192, 2014

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