4M1D
Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 cyclic peptide MN
Summary for 4M1D
Entry DOI | 10.2210/pdb4m1d/pdb |
Descriptor | Fab mAb 447-52D Light Chain, Fab mAb 447-52D Heavy Chain, Cyclic V3 Arch Peptide, ... (5 entities in total) |
Functional Keywords | hiv, v3 loop, antibody-antigen interactions, envelope, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 99861.45 |
Authors | Killikelly, A.,Kong, X.P. (deposition date: 2013-08-02, release date: 2013-09-04, Last modification date: 2024-10-09) |
Primary citation | Killikelly, A.,Zhang, H.T.,Spurrier, B.,Williams, C.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P. Thermodynamic Signatures of the Antigen Binding Site of mAb 447-52D Targeting the Third Variable Region of HIV-1 gp120. Biochemistry, 52:6249-6257, 2013 Cited by PubMed: 23944979DOI: 10.1021/bi400645e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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